副腎皮質ホルモン剤常用の潰瘍性大腸炎患者に発生した下唇癌の1例

• 植田 章夫

  Department of Oral and Maxillofacial Surgery I, Matsumoto Dental College

• 中嶌 哲

  Department of Oral and Maxillofacial Surgery I, Matsumoto Dental College

• 川上 敏行

  Department of Oral Pathology, Matsumoto Dental College

• 千野 武廣

  Department of Oral and Maxillofacial Surgery I, Matsumoto Dental College

書誌事項

タイトル別名

• Report pf a case-Carcinoma of the lower lip occured ulcerative colitis patient under the administration of steroid hormones over extend period of time

抄録

Steroid hormones have immunosuppressive and anti-inflammatory properties. Therefore, the drugs administered in the treatment of many diseases. Recently, we had the experience of treating the case of a 37 year old female patient with lip carcinoma. This patient had been prescribed steroid hormone for treatment of her ulcerative colitis extend over a long period time. She was admitted to our clinic for treatment of a lower lip ulcer. The clinical findings suggested that malignant neoplasmus, however some consideration was given to the possibility that the lip ulcer was complication of the ulcerative colitis and that the healing of the wound was affected negatively by the immunosuppress property of the steroid hormone. Therefore, antiulcerative ointment was applied locally. But the ulcerative legion began to increase in size so a biopsy was performed quickly. Histopathological diagnosis was squamous cell carcinoma, so after the radiotherapy tumor excision, bilateral supraomohyoid neck dissection and immediate reconstruction using forearm skin flap was performed. Postoperative course was uneventful, although the patient noticed some stiffness in the left upper neck region. Through the use of a CT examination, a metastatic legion in a deep part of the cervical lymph-node was suspected. A radical neck dissection was performed in the usual manner. One month after the operation, multiple metastasis occurred in the cervical and temporal regions, the lung and the acetabulum.<BR>This case suggests there is the possibility that increasing incidence of metastasis occures in immunosuppressed patients.

収録刊行物

• 有病者歯科医療

  有病者歯科医療 5 (2), 126-131, 1997

  一般社団法人 日本有病者歯科医療学会

詳細情報

• CRID: 1390001204485770240
• NII論文ID: 130004102830
• DOI: 10.11255/jjmcp1992.5.126
• ISSN: 1884667X
• ISSN: 09188150
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可