書誌事項
- タイトル別名
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- Sodium Carbonate is a Useful New Preservative for Collecting 24-hr Urine Samples to Measure Urinary C-peptide
- ニョウチュウ C-ペプチド ソクテイヨウ ノ チクニョウジ テンカザイ ト シテ ノ タンサン ナトリウム セイザイ ノ ケントウ
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The amount of urinary C-peptide (U-CPR) is a good parameter for estimating the insulin secretory ability of diabetic patients. However, a preservative must be added to urine samples to prevent reductions in the CPR level. Sodium azide (NaN3) is a routinely used preservative, but its use and handling are strictly controlled. A new preservative, composed mainly of Na2CO3, has been developed as a safer preservative. We examined the effects of this new preservative by comparing the 24-hr U-CPR levels obtained at 4°C and 28°C with or without NaN3 or Na2CO3. The C-peptide level was measured using two commercially available assay kits. The levels of U-CPR in urine samples kept at 28°C and containing Na2CO3 were well correlated with the levels of U-CPR in samples kept at 4°C and were higher than those in any other sample. Among the other urine components commonly measured by laboratories, urea nitrogen, creatinine and chloride were measured without any interference. This newly-eveloped preservative was therefore found to be a useful alternative to NaN3 for the accurate measurement of U-CPR levels.
収録刊行物
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- 糖尿病
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糖尿病 46 (12), 919-924, 2003
一般社団法人 日本糖尿病学会
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詳細情報 詳細情報について
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- CRID
- 1390282679882891776
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- NII論文ID
- 130004115382
- 10012731189
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- NII書誌ID
- AN00166576
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- ISSN
- 1881588X
- 0021437X
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- NDL書誌ID
- 025099795
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可