胆石症を併存したＤｕｂｉｎ‐Ｊｏｈｎｓｏｎ症候群の１例

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  • A case report of Dubin-Johnson syndrome with gallstones.

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We had one cholecystectomied case of Dubin Johnson syndrome (D-J syndrome) complicated with gallstones, a 35 year old man with jaundice and right hypochondralgia. His common bile duct and gallbladder were visualized by Drip Infusion Cholecystocholangiography (DIC), but no gallstones appeared. Ultrasonography showed a strong echo with acoustic shadow in the gallbladder, which on cholecystectomy contained 327 cholesterol gallstones. They consisted of more than 98% cholesterol. His postoperative liver function was almost the same as the preoperative one. On the 3rd postoperative day his maximum level of serum total bilirubin and direct bilirubin were 5.6 mg/dl, 4.0 mg/dl respectively. His postoperative course was uneventful. A total of 24 such cases are reported in Japan to 1988, including our case. In these cases, younger generation from 10 to 29 years old is more frequently complicated with gallstones, compared with the same generation of operated gallstone cases without D-J syndrome. When patients with D-J syndrome complain of abdominal pain, it is important to check for gallstones by ultrasonography at first too.

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