産婦人科領域における T-1982 (Cefbuperazone) の体内移行並びに臨床応用 [in Japanese] FUNDAMENTAL AND CLINICAL STUDIES ON T-1982 (CEFBUPERAZONE) IN THE FIELD OF OBSTETRICS AND GYNECOLOGY [in Japanese]
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富山化学工業 (株) と科研製薬 (株) で共同開発したT-1982 (Cefbuperazone) 1) の臨床価値を意義づけるため, 産婦人科領域における体内移行並びに臨床成績を検討したので報告する。
T-1982 (cefbuperazone), a new cephamycin antibiotic, was fundamentally and clinically studied in the field of obstetrics and gynecology.<BR>The following results were obtained.<BR>1. The concentrations of T-1982 in arterial and venous blood and genitalia following intravenous injection were measured. The results demonstrated favourable transfer of the drug into various internal genital organs.<BR>2. T-1982 was administered to 12 patients. The efficacy rate was 75.0%, that is to say, good in 9 cases. No side effects were noted in any cases.<BR>It is, therefore, presumed that T-1982 is a useful drug for the infectious diseases in the field of obstetrics and gynecology although the number of subjects was not so large in this study.
- The Japanese Journal of Antibiotics
The Japanese Journal of Antibiotics 36(5), 1061-1072, 1983
Japan Antibiotics Research Association