Optical Resolution of Amino Acid Esters by <i>N</i>-Protected Aspartylphenylalanine Esters
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- Kiyotaka Oyama
- Chemical Research Center, Tosoh Corporation
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- Mikio Itoh
- Chemical Research Center, Tosoh Corporation
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- Yuji Nonaka
- Chemical Research Center, Tosoh Corporation
抄録
<jats:title>Abstract</jats:title> <jats:p>A new method was studied for optical resolution of racemic amino acid esters by using, as resolving agents, N-protected l-α-aspartyl-l-phenylalanine alkyl esters, typically, N-benzyloxycarbonyl-l-α-aspartyl-l-phenylalanine methyl ester, the precursor to the synthetic sweetener aspartame. Thus, when the dipeptide and racemic amino acid ester were mixed in solvents, precipitation took place by formation of salt preferentially with d-amino acid ester to effect the optical resolution.</jats:p>
収録刊行物
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- Bulletin of the Chemical Society of Japan
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Bulletin of the Chemical Society of Japan 65 (7), 1751-1754, 1992-07-01
Oxford University Press (OUP)
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キーワード
詳細情報 詳細情報について
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- CRID
- 1360002219103700480
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- NII論文ID
- 130004147804
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- ISSN
- 13480634
- 00092673
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- データソース種別
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