雀啄・捻鍼による鍼鎮痛過程に関する末梢機序

DOI Web Site 被引用文献1件
  • 橋本 辰幸
    北里大学 衛生学部 生理学教室 全日本鍼灸学会 神奈川地方会
  • 相川 貞男
    北里大学 衛生学部 生理学教室 全日本鍼灸学会 神奈川地方会

書誌事項

タイトル別名
  • Manual acupuncture and its peripheral mechanisms: involvement of nociceptors in muscle.
  • 雀啄・捻鍼による鍼鎮痛過程に関する末梢機序〔英文〕
  • ジャクタク ネン シン ニ ヨル ハリ チンツウ カテイ ニ カンスル マッシ
  • involvement of nociceptors in muscle

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抄録

Peripheral mechanisms that induce analgesic effects in manual acupuncture were studied in urethane-anesthetized rats. Unitary extracellular recordings were made from spinal wide dynamic range (WDR) neurons and repetitive electrical stimuli were delivered to the excitatory receptive fields to determine a noxious index. First, the analgesic effects of manual acupuncture and a noxious pinch to the skin (Diffuse Noxious Inhibitory Controls: DNIC) were compared. Second, manual acupuncture was applied to different structures at the acupuncture point, such as the skin, skin plus muscle, and muscle. In a third experiment, the analgesic effects of intramuscular injection of 4.5% NaCl and manual acupuncuture were compared. Manual acupuncture and a noxious pinch exhibited a very similar time course and magnitude of inhibitory effects on C-evoked discharges. As for differential stimulation of the acupuncture point, application of the needle to the skin only was less effective than to the skin plus muscle or the muscle only. Both intramuscular injection of 4.5% NaCl and manual acupuncture reduced C-evoked discharges while injection of isotonic saline produced almost no inhibitory effects. These data suggest that application of manual acupuncture might arouse noxious sensations that result in activating pain inhibitory processes. Moreover, it is thought that excitation of polymodal receptors in the muscle is a critical factor in inducing analgesic effects in manual acupuncture.

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