Coronary Artery Spasm as Revealed by Morphological Methodology

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  • 形態学的方法からみた冠状動脈の攣縮現象

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Abstract

The present study revealed the images of the coronary artery spasm morphologically using the experimental model of the coronary artery spasm. Rat heart tissues injected with endothelin solution were studied by scanning and transmission electron microscopy. In the coronary arteries, smooth muscle cells and the internal elastic lamina showed peculier images suggestive of spasm, and the endothelial cells were also damaged. The lumen of both arterioles and capillaries became narrow. Some of cardiac myocytes were characterized by the presence of swollen mitochondria, disarrangement of myofibrils and separation of intercalated discs. From the nursing point of view, morphological images of the coronary artery spasm obtained by us may be situated as a fundamental study to exhibit reactions in living condition.

Journal

  • Structure and Function

    Structure and Function 2 (1), 3-9, 2003

    Co-medical Research Society of Structure and Function

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