泌尿器科領域におけるCefuroxime axetil (CXM-AX) の臨床的検討

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  • CLINICAL STUDIES ON CEFUROXIME AXETIL (CXM-AX) IN THE UROLOGY

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Cefuroxime axetil (CXM-AX, SN 407), an oral cephalosporin, was administered to patients with urinary tract infections, and its clinical efficacy and safety were evaluated.<BR>250 mg-500 mg t. i. d. of CXM-AX was given after meals, for consecutive 7-15 days. A total of 26 patients were treated, i. e. 23 with acute uncomplicated cystitis, 2 with gonorrheal urethritis and 1 with acute prostatitis.<BR>The overall clinical efficacy assessed by the doctors in charge was as follows; among acute uncomplicated cystitis cases, 16 cases as excellent, 6 good and 1 fair (efficacy rate: 95.7%), 2 cases of gonorrheal urethritis as good and 1 case of acute prostatitis as poor.<BR>The clinical efficacy evaluated according to the “Criteria for Evaluation of Clinical Efficacy of Antimicrobial Agents on UTI” in 9 cases of acute uncomplicated cystitis was; excellent in 8 and good in 1, the efficacy rate being 100%.<BR>The only side effect noted was mild nausea in one patient. Abnormal laboratory findings were not observed in any patient.

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