フェロー諸島における出生コホート研究

• 村田 勝敬

  秋田大学医学部社会環境医学講座環境保健学分野

• 嶽石 美和子

  秋田大学医学部社会環境医学講座環境保健学分野

• 岩田 豊人

  秋田大学医学部社会環境医学講座環境保健学分野

書誌事項

タイトル別名

• A lesson from the Faroese birth cohort study

抄録

Because methylmercury accumulates in aquatic and marine food chains, recent research has focused on adverse effects of dietary exposures in humans and on the concentration levels that may affect the progeny of the exposed population. Following the outbreaks of methylmercury poisoning in Japan and Iraq, large-scale follow-up studies were carried out in the Faroe Islands, Seychelles and New Zealand, to clarify the effects of prenatal methylmercury exposure on child neurodevelopment. This review outlines the experience obtained in the Faroese birth cohort study. Mercury exposures among the children in the study were assessed through analyses of cord blood samples at birth and hair samples taken at ages 7 and 14. Significant dose-effect relationships between prenatal methylmercury exposures and both neurobehavioral and neurophysiological endpoints were observed; also, several potential sources of bias or confounders have been considered. Their main effect seems to be an underestimation of the true neurotoxic effect of developmental methylmercury. This evidence suggests that underestimation may also affect the findings of other studies in this field.

収録刊行物

• 環境科学会誌

  環境科学会誌 17 (3), 169-180, 2004

  社団法人 環境科学会

キーワード

• メチル水銀,小児の発達,リスクアセスメント,フェロー出生コホート研究

詳細情報

• CRID: 1390282679397396608
• NII論文ID: 130004304098
• DOI: 10.11353/sesj1988.17.169
• ISSN: 18845029
• ISSN: 09150048
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可