大腸癌の肝転移巣切除症例の検討

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  • Hepatic Resection for Metastases from Colorectal Carcinoma.

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From January 1982 to September 1993, 27 patients with hepatic metastases from colorectal carcinoma underwent hepatic resection at Nagasaki Chuo National Hospital.<br>Hepatic resection of these 27 patients consisted of 5 right hepatectomies, two left lobectomies, 4 left lateral segmentectomies, 4 mono- or di-segmentectomies, and twelve subsegmentectomies and/or partial resections. Hepatic metastases were H-1 in 19 patients and H-2, 3 in 8.<br>After hepatic resection, five-year survival rate of H-1 patients (30.5%) was siginificantly higher than that of H-2, 3 patients (0%) (p<0.05). There were no significant differences in site of colorectal carcinoma, size of largest tumor, temporal relation, histological type and DNA ploidy pattern of parimary and metastatic lesion in five-year survival rate. Of these 27 patients, 5 survived for more than 3 years. In these 5 patients, the metastases were metachronous in 2 and synchronous in 3, the primary lesions were located in sigmoid colon in 4 and rectum in 1, and the degree of metastases were H-1 in all 5. The DNA ploidy pattern of metastatic lesion was diploid pattern (D) in 3 and aneuplod pattern (A) in 2, and that of the primary lesion was D in 2 and A in 2. Two of the 5 patients received hepatic re-resection for re-recurrence. All patients who did not undergo hepatic resection for the metastatic lesions died within 3 years.<br>From these observations, the prognosis of hepatic resection for metastatic colorectal carcinoma with H-1 is considered to be favorable, and aggressive hepatic resection is recommended

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  • 医療

    医療 48 (10), 801-808, 1994

    一般社団法人 国立医療学会

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