糖尿病患者のヘモグロビンAIC

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タイトル別名
  • Hemoglobin Mc Concentrations in Untreated Diabetics and Changes after One Month's Treatment
  • トウニョウビョウ カンジャ ノ ヘモグロビン AIC トクニ ミ チリョウジ
  • とくに未治療時および治療1ヵ月後の値について

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抄録

The relationship between the HbAic and blood glucose levels of untreated diabetics, and the changes in HbAic after one month's treatment, were studied.<BR>The results obtained were as follows.<BR>1) The HbAic concentrations in untreated diabetics (11.18±2.27, mean±SD, percent of total hemoglobin) were significantly higher than those of normal subjects (5.32±0.63%, p<0.001).<BR>2) The concentrations of HbAic in untreated diabetics were correlated with the fasting blood glucose levels measured on the same samples (r=0.51, p<0.001).<BR>3) HbAic concentrations were closely associated with blood glucose levels at 1 hr and 2 hr of oral glucose tolerance tests (r=0.39, p<0.05; r=0.42, p<0.02, respectively).<BR>The HbAic levels before and after diabetic treatment were compared in 19 diabetics (taken from a group of 43 untreated diabetics) who were measured for HbAic after 1 month's treatment, and in 6 patients who were changed to an alternative treatment due to poor control.<BR>The results obtained were as follows.<BR>1) After 1 month's treatment, the decrease in HbAic was similar in all cases where the blood glucose level had dropped to the same extent, whether treated with diet alone, sulfonylurea or insulin.<BR>2) After 1 month's treatment, the decrease in HbAic was slower in patients with retinopathy than in those without retinopathy.<BR>These findings indicated that the concentrations of HbAic in the untreated diabetics fully reflected the degree of hyperglycemia at that time.<BR>The decrement of HbAic levels after 1 month's treatment was similar among the three kinds of therapy, but was slower in the diabetics with retinopathy than in those without.

収録刊行物

  • 糖尿病

    糖尿病 23 (3), 201-208, 1980

    一般社団法人 日本糖尿病学会

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