名古屋市における経口血糖降下剤およびインスリンによる重症低血糖の実態調査

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タイトル別名
  • Results of an Inquiry into the Clinical Features of Severe Hypoglycemia Due to Oral Hypoglycemic Drugs or Insulin in Nagoya City
  • ナゴヤシ ニ オケル ケイコウ ケットウ コウカザイ オヨビ インスリン ニヨ

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抄録

The number and causes of severe hypoglycemic cases among diabetic patients during the past one year due to oral hypoglycemic drugs and insulin in Nagoya City were investigated by sending questionnaires to 521 physician's offices and 115 hospitals. 39.3% of the questionnaires were answered. 5868 cases of diabetic patients were included in the present study. The frequency of severe hypoglycemia was 0.31% among patients treated with oral hypoglycemic drugs and 1.27% among those treated with insulin. The percentage of severe hypoglycemia due to oral hypoglycemic drugs was lower than that reported by Yuchi in 1975 (1.36%). However, the patients managed by insulin were more or less equal to the percentage reported by Yuchi in 1975 (1.53%). The major cause of the severe hypoglycemia due to oral hypoglycemic drugs was inappropriate drug therapy by doctors. The major cause of the severe hypoglycemia due to insulin in the present study was insufficient intake of diet. Lack of proper education of patients about hypoglycemia and carelessness regarding hypoglycemia by both doctors and patients were also resposible for severe hypoglycemia due to insulin. The finding that seven out of eight cases of severe hypoglycemia due to oral hypoglycemic drugs were patients aged over 70 years emphasized the special attention needed in the therapy of oral hypoglycemic drugs in elderly patients. The body weights of patients with severe hypoglycemia due to insulin were light, indicating that lean patients were more liable to suffer from insulin hypoglycemia. A questionnaire concerning the injection modality of insulin in diabetic patients revealed that self-administration of insulin by patients was far more frequent than administration by doctors and nurses. However, severe hypoglycemia due to insulin occurred equally in self-injected Patients and in those injected by doctors or nurses. This clearly shows that the frequency of severe hypoglycemia due to insulin was smaller in patients undergoing selfinjection than that those receiving injections from doctors and nurses.

収録刊行物

  • 糖尿病

    糖尿病 24 (4), 463-468, 1981

    一般社団法人 日本糖尿病学会

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