Ｗｅｇｅｎｅｒ肉芽しゅ症症例の側頭骨病理所見

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  • Temporal bone pathology in Wegener's granulomatosis.

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The temporal bone of the patient, a 44-year-old woman, who was diagnosed as Wegener's granulomatosis was studied. Her audiogram showed the severe perceptive deafness of both ears. The right temporal bone had many interesting changes. The tympanic cavity, mastoid air cells and eustachian tube were filled with granulation tissue. The crura of the stapes were damaged and foot plate was covered and thinned by granulation tissue. The granulation tissue invaded into the round window niche. The round window membrane swelled and jutted out into the scala tympani. Reissner's membrane and basilar membrane were torn at the basal and middle turns of the right cochlea, and the endolymph-perilymph fistulae were formed. Severe degeneration of the hair cell of the organ of Corti was seen at the site of the fistulae, and light degeneration of the stria vascularis.

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