急性陰窩性扁桃炎に対するCefuroxime axetilの薬効評価
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- 河村 正三
- Department of Otorhinolaryngology, Juntendo University, School of Medicine
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- 古内 一郎
- Department of Otorhinolaryngology, Dokkyo University, School of Medicine
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- 谷垣内 由之
- Department of Otorhinolaryngology, Dokkyo University, School of Medicine
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- 藤巻 豊
- Department of Otorhinolaryngology, Katsunan Hospital
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- 板橋 隆嗣
- Department of Otorhinolaryngology, Koto Hospital
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- 渡辺 洋
- Department of Otorhinolaryngology, Taketani Hospital
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- 堀川 治久
- Horikawa Clinic of Otorhinolaryngology
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- 野村 恭也
- Department of Otorhinolaryngology, Faculty of Medicine, University of Tokyo
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- 川端 五十鈴
- Department of Otorhinolaryngology, Faculty of Medicine, University of Tokyo
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- 庄司 稔
- Department of Otorhinolaryngology, Faculty of Medicine, University of Tokyo
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- 市村 恵一
- Department of Otorhinolaryngology, Tokyo Metropolitan Fuchu Hospital
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- 周 明仁
- Department of Otorhinolaryngology, Tokyo Metropolitan Fuchu Hospital
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- 村上 泰
- Department of Otorhinolaryngology, Tokyo Metropolitan Fuchu Hospital
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- 三宅 浩郷
- Department of Otorhinolaryngology, Tokai University, School of Medicine
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- 新川 敦
- Department of Otorhinolaryngology, Tokai University, School of Medicine
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- 松川 純一
- Department of Otorhinolaryngology, Nihon Kokan Hospital
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- 簡 志明
- Department of Otorhinolaryngology, Nihon Kokan Hospital
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- 木村 栄成
- Department of Otorhinolaryngology, Nihon Kokan Hospital
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- 坂井 真
- Department of Otorhinolaryngology, Tokai University, Tokyo Hospital
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- 小松 信行
- Department of Otorhinolaryngology, Tokai University, Tokyo Hospital
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- 安藤 真姿子
- Department of Otorhinolaryngology, Tokai University, Tokyo Hospital
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- 秋田谷 直
- Department of Otorhinolaryngology, Kosei Hospital
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- 田村 嘉之
- Department of Otorhinolaryngology, Kosei Hospital
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- 飯田 政弘
- Department of Otorhinolaryngology, Isehara Kyodo Hospital
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- 中山 むつみ
- Department of Otorhinolaryngology, Isehara Kyodo Hospital
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- 馬場 駿吉
- Department of Otorhinolaryngology, Nagoya City University, School of Medicine
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- 島田 純一郎
- Department of Otorhinolaryngology, Nagoya City University, School of Medicine
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- 征矢野 薫
- Department of Otorhinolaryngology, Nagoya City University, School of Medicine
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- 森 慶人
- Department of Otorhinolaryngology, Nagoya City University, School of Medicine
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- 鈴木 賢二
- Department of Otorhinolaryngology, Nagoya City University, School of Medicine
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- 稲垣 光昭
- Department of Otorhinolaryngology, Nagoya City University, School of Medicine
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- 大屋 靖彦
- Department of Otorhinolaryngology, Nagoya Municipal Midori City Hospital
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- 本堂 潤
- Department of Otorhinolaryngology, Nagoya Second Red Cross Hospital
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- 高木 一平
- Department of Otorhinolaryngology, Nagoya Second Red Cross Hospital
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- 月山 昌夫
- Department of Otorhinolaryngology, Tokai Teishin Hospital
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- 高野 剛
- Department of Otorhinolaryngology, Kasugai City Hospital
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- 河合 孝
- Department of Otorhinolaryngology, Ichinomiya City Hospital
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- 木下 治二
- Department of Otorhinolaryngology, Atsumi Hospital
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- 丸尾 猛
- Department of Otorhinolaryngology, Showa Hospital
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- 伊藤 晴夫
- Department of Otorhinolaryngology, Showa Hospital
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- 森戸 貞良
- Department of Otorhinolaryngology, Kainan Hospital
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- 伊藤 弘美
- Department of Otorhinolaryngology, Kainan Hospital
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- 和田 正樹
- Department of Otorhinolaryngology, Kamo Hospital
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- 波多野 努
- Department of Otorhinolaryngology, Toyohashi City Hospital
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- 加藤 真二
- Department of Otorhinolaryngology, Toyohashi City Hospital
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- 北垣 徹
- Department of Otorhinolaryngology, Toyohashi City Hospital
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- 鈴木 康夫
- Department of Otorhinolaryngology, Toyokawa City Hospital
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- 岩田 重信
- Department of Otorhinolaryngology, Fujita Gakuen Health University, School of Medicine
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- 八木沢 幹夫
- Department of Otorhinolaryngology, Fujita Gakuen Health University, School of Medicine
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- 高須 昭彦
- Department of Otorhinolaryngology, Fujita Gakuen Health University, School of Medicine
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- 八井田 昌志
- Department of Otorhinolaryngology, Gamagori City Hospital
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- 松永 亨
- Department of Otorhinolaryngology, Osaka University, Medical Scho6l
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- 荻野 仁
- Department of Otorhinolaryngology, Osaka University, Medical Scho6l
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- 入船 盛弘
- Department of Otorhinolaryngology, Osaka University, Medical Scho6l
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- 大川内 一郎
- Department of Otorhinolaryngology, Osaka Central Hospital
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- 川嵜 良明
- Department of Otorhinolaryngology, Osaka Teishin Hospital
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- 奥村 新一
- Department of Otorhinolaryngology, Osaka Rosai Hospital
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- 土井 勝美
- Department of Otorhinolaryngology, Osaka Rosai Hospital
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- 杉本 和彦
- Department of Otorhinolaryngology, Osaka Rosai Hospital
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- 佐藤 信次
- Department of Otorhinolaryngology, Otemae Hospital
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- 石田 稔
- Department of Otorhinolaryngology, Suita Municipal Hospital
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- 田矢 直三
- Department of Otorhinolaryngology, Suita Municipal Hospital
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- 尾崎 正義
- Department of Otorhinolaryngology, Toyonaka City Hospital
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- 金 昌信
- Department of Otorhinolaryngology, Toyonaka City Hospital
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- 小田 隆造
- Department of Otorhinolaryngology, Meiwa Hospital
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- 前田 英雄
- Department of Otorhinolaryngology, Meiwa Hospital
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- 三好 敏之
- Department of Otorhinolaryngology, Minoo City Hospital
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- 原田 康夫
- Department of Otorhinolaryngology, Hiroshima University, School of Medicine
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- 夜陣 紘治
- Department of Otorhinolaryngology, Hiroshima University, School of Medicine
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- 平川 勝洋
- Department of Otorhinolaryngology, Hiroshima University, School of Medicine
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- 竹林 脩文
- Department of Otorhinolaryngology, Hiroshima Prefectural Hospital
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- 和田 秀毅
- Department of Otorhinolaryngology, Hiroshima Prefectural Hospital
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- 築家 大介
- Department of Otorhinolaryngology, Hiroshima General Hospital
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- 中田 将風
- Department of Otorhinolaryngology, Kure National Hospital
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- 野田 益弘
- Department of Otorhinolaryngology, Hiroshima Red Cross Hospital
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- 黒川 道徳
- Department of Otorhinolaryngology, Onomichi General Hospital
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- 村上 譲
- Department of Otorhinolaryngology, Mitsubishi Mihara Hospital
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- 菊屋 義則
- Department of Otorhinolaryngology, Chugoku Rosai Hospital
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- 二宮 優子
- Department of Otorhinolaryngology, Yoshida general Hospital
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- 大山 勝
- Department of Otorhinolaryngology, Faculty of Medicine, Kagoshima University
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- 矢野 博美
- Department of Otorhinolaryngology, Faculty of Medicine, Kagoshima University
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- 清田 隆二
- Department of Otorhinolaryngology, Kagoshima Prefectural Hokusatsu Hospital
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- 田渕 えり子
- Department of Otorhinolaryngology, Ichihino Onsen Hospital
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- 松山 博文
- Department of Otorhinolaryngology, Miyanojo Central Hospital
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- 深水 浩三
- Department of Otorhinolaryngology, Kokubu Central Hospital
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- 大野 郁夫
- Department of Otorhinolaryngology, Kagoshima Prefectural Ohshima Hospital
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- 中島 光好
- Department of Pharmacology, Hamamatsu University, School of Medicine
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- 出口 浩一
- Tokyo clinical Research Center
書誌事項
- タイトル別名
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- Clinical Evaluation of Cefuroxime Axetil in Acute Tonsillitis
- A Double Blind Comparison with Cefaclor
- 二重盲検法によるCefaclorとの比較試験
抄録
A double blind comparative study was performed on cefuroxime axetil (CXM-AX), to evaluate objectively its efficacy, safety and usefulness in acute tonsillitis, using cefaclor (CCL) as the comparator. Either of the drugs was administered in the dose of 250 mg tid., in principle for 7 days.<BR>1. In the evaluation of clinical efficacy, the efficacy rates of CXM-AX and CCL were 90.5% (95/105) and 88.2% (90/102), respectively, in the assessment by doctors in charge, and 88.6% (93/105) and 87.3% (89/102), respectively, in the assessment by the committee, without statistically significant difference between the two treatment groups.<BR>2. When the bacteriological response was evaluated in each case, the elimination rate was 98.0% (96/ 98) in CXM-AX group and 98.9% (91/92) in CCL group, and there was no significant difference between the two groups either in this comparison or in the evaluation on the bacteriological response classified by causative organisms.<BR>3. In overall safety, no significant difference was observed between two treatment groups. Adverse events, all of which were gastrointestinal tract symptoms, were observed in 2.6% (3/114) in CXM-AX group, and in 2.7% (3/111) in CCL group. Either in adverse events or abnormal laboratory findings, the difference in incidences was not statistically significant between the two groups.<BR>4. The usefulness rates of CXM-AX and CCL were 93.3% (98/105) and 91.2% (93/102), respectively, with no significant difference. The above results suggest that CXM-AX is a very useful drug for the treatment of acute tonsillitis.
収録刊行物
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- 耳鼻と臨床
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耳鼻と臨床 33 (3), 434-451, 1987
JIBI TO RINSHO KAI
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詳細情報 詳細情報について
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- CRID
- 1390282680476322560
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- NII論文ID
- 130004403270
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- ISSN
- 04477227
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
