A clinical trial of E0659 nasal gel spray on perennial allergic rhinitis
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- OKUDA Minoru
- Japan Allergy and Asthma Clinic
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- TAKASAKA Tomonori
- Department of Otorhinolaryngology, Tohoku University, School of Medicine
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- INAMURA Naoki
- Department of Otorhinolaryngology, Tohoku University, School of Medicine
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- SATO Mitsuyoshi
- Department of Otorhinolaryngology, Tohoku University, School of Medicine
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- HASHIMOTO Syo
- Department of Otorhinolaryngology, National Sendai Hospital
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- AWATAGUCHI Toshiichi
- Department of Otorhinolaryngology, Tohoku Koseinenkin Hospital
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- OYAMA Kenji
- Department of Otorhinolaryngology, Tohoku Rousai Hospital
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- SUZUKI Masaaki
- Department of Otorhinolaryngology, NTT Tohoku Hospital
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- SAKURADA Takashi
- Department of Otorhinolaryngology, Furukawa City General Hospital
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- ENDO Satomi
- Department of Otorhinolaryngology, Yamagata City Hospital Saiseikan
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- ISHITOYA Masako
- Department of Otorhinolaryngology, Yamagata City Hospital Saiseikan
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- OSHIMA Takeshi
- Department of Otorhinolaryngology, Nagai Municipal General Hospital
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- NAKANO Hiroshi
- Department of Otorhinolaryngology, Nagai Municipal General Hospital
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- MESHIZUKA Keisuke
- Department of Otorhinolaryngology, Japanese Red Cross Medical Center
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- ICHIKAWA Tomoya
- Department of Otorhinolaryngology, Japanese Red Cross Medical Center
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- FUKAYA Takashi
- Department of Otorhinolaryngology, Kanto Teisin Hospital
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- ITO Yoriko
- Department of Otorhinolaryngology, Kanto Teisin Hospital
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- YOSHIDA Katsuya
- Department of Otorhinolaryngology, Kanto Teisin Hospital
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- KOBAYASHI Keiko
- Department of Otorhinolaryngology, Kanto Teisin Hospital
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- WADA Masashi
- Department of Otorhinolaryngology, Tokyo Rousai Hospital
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- YAMAGUCHI Hiroya
- Department of Otorhinolaryngology, Tokyo Senbai Hospital
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- OGAWA Yutaka
- Department of Otorhinolaryngology, Kosei General Hospital
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- ZUSHO Hiroyuki
- Department of Otorhinolaryngology, Kanto Rousai Hospital
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- FUJII Issei
- Department of Otorhinolaryngology, Nihon-Kokan Hospital
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- FUKUSATO Hiroshi
- Department of Otorhinolaryngology, Nihon-Kokan Hospital
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- OKAMOTO Kazuhito
- Department of Otorhinolaryngology, Yokohama Rousai Hospital
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- MORISONO Tetsushi
- Department of Otorhinolaryngology, Yatsu Hoken Hospital
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- YAMAKOSHI Takayuki
- Department of Otorhinolaryngology, Chosei Hospital
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- KATAGIRI Jun-ichi
- Department of Otorhinolaryngology, Matsudo Municipal Hospital
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- OHASHI Kazushi
- Department of Pharmacology, Nippon Medical School
Bibliographic Information
- Other Title
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- E0659点鼻ゲルの通年性アレルギー性鼻炎に対する臨床的検討
- 用法検討試験
Abstract
To determine the optimal regimen for E0659 nasal gel spray in perennial allergic rhinitis, a multicenter single-blind study was carried out by administering E0659 15μgispray in both b.i.d. and t.i.d. regimens,<BR>1. The final global improvement rating was 52% for the b.i.d. group and 43% for the t.i.d. group, based on “good to excellent” responses. Therefore, the result between the b.i.d. and the t.i.d. regimens were considered to be clinically similar.<BR>2. The overall safety rating based on “no safety problems” was 97% for b.i.d. and 98% for the t.i.d. group, so no difference in the overall safety rating was observed between the b.i.d. and the t.i.d. regimens.<BR>3. The utility rating was 57% for the b.i.d. group and 48% for the t.i.d. group based on a finding of “useful to very useful”, so again the findings for the b.i.d. and t.i.d.regimens were found to be similar.<BR>Based on the above findings, the b.i.d. treatment regimen is therefore considered to be the optimal regimens for E0659 nasal spray.
Journal
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- OTOLOGIA FUKUOKA
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OTOLOGIA FUKUOKA 42 (2), 184-202, 1996
JIBI TO RINSHO KAI
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Keywords
Details 詳細情報について
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- CRID
- 1390282680476222080
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- NII Article ID
- 130004404232
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- ISSN
- 04477227
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed
