DNA Hydrolysis by Cerium(IV) Does Not Involve either Molecular Oxygen or Hydrogen Peroxide

• Makoto Komiyama

  Department of Industrial Chemistry, Faculty of Engineering, University of Tokyo

• Tetsuro Shiiba

  Department of Industrial Chemistry, Faculty of Engineering, University of Tokyo

• Teruyuki Kodama

  Department of Industrial Chemistry, Faculty of Engineering, University of Tokyo

• Naoya Takeda

  Department of Industrial Chemistry, Faculty of Engineering, University of Tokyo

• Jun Sumaoka

  Department of Industrial Chemistry, Faculty of Engineering, University of Tokyo

• Morio Yashiro

  Department of Industrial Chemistry, Faculty of Engineering, University of Tokyo

抄録

DNA hydrolysis by Ce(IV) effectively proceeds both in the presence and in the absence of molecular oxygen. Addition of hydrogen peroxide induces undesired oxidative side-reactions and suppresses the hydrolysis. Participation of molecular oxygen and hydrogen peroxide in the phosphodiester hydrolysis is ruled out, supporting the intramolecular attack by the Ce(IV)-bound hydroxide ion.

収録刊行物

• Chemistry Letters

  Chemistry Letters 23 (6), 1025-1028, 1994-06-01

  Oxford University Press (OUP)

キーワード

• General Chemistry

詳細情報

• CRID: 1360846644038975616
• NII論文ID: 130004419477
• DOI: 10.1246/cl.1994.1025
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/23/6/1025/56065913/cl.1994.1025.pdf
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