Indium(III)-catalyzed Coupling between Alkynes and Aldehydes to α,β-Unsaturated Ketones

• Katsukiyo Miura

  Department of Applied Chemistry, Graduate School of Science and Engineering, Saitama University

• Kiyomi Yamamoto

  Department of Chemistry, Graduate School of Pure and Applied Sciences, University of Tsukuba

• Aya Yamanobe

  Department of Chemistry, Graduate School of Pure and Applied Sciences, University of Tsukuba

• Keisuke Ito

  Department of Chemistry, Graduate School of Pure and Applied Sciences, University of Tsukuba

• Hidenori Kinoshita

  Department of Applied Chemistry, Graduate School of Science and Engineering, Saitama University

• Junji Ichikawa

  Department of Chemistry, Graduate School of Pure and Applied Sciences, University of Tsukuba

• Akira Hosomi

  Department of Chemistry, Graduate School of Pure and Applied Sciences, University of Tsukuba

抄録

The combined use of a catalytic amount of InX3 (X = OTf and NTf2) and 1-butanol was found to be effective in formal alkyne–aldehyde metathesis. With this catalytic system, aromatic alkynes reacted with aromatic aldehydes to give chalcones in moderate to good yields. Alkynals were efficiently converted into 5- to 7-membered cyclic compounds by intramolecular alkyne–aldehyde coupling.

収録刊行物

• Chemistry Letters

  Chemistry Letters 39 (7), 766-767, 2010-06-12

  Oxford University Press (OUP)

キーワード

• General Chemistry

詳細情報

• CRID: 1360283694088160640
• NII論文ID: 130004425911
• DOI: 10.1246/cl.2010.766
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/39/7/766/55603415/cl.2010.766.pdf
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