Nickel-catalyzed Heteroannulation of <i>o</i>-Haloanilines with Alkynes

  • Yuji Yoshida
    Department of Material Chemistry, Graduate School of Engineering, Kyoto University
  • Takuya Kurahashi
    Department of Material Chemistry, Graduate School of Engineering, Kyoto University
  • Seijiro Matsubara
    Department of Material Chemistry, Graduate School of Engineering, Kyoto University

Abstract

<jats:title>Abstract</jats:title> <jats:p>A nickel-catalyzed heteroannulation has been developed where o-haloanilines react with alkynes to afford 2,3-disubstituted indoles. IPr (1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) was found to be an effective ligand for the reaction.</jats:p>

Journal

  • Chemistry Letters

    Chemistry Letters 40 (10), 1067-1068, 2011-09-17

    Oxford University Press (OUP)

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