Synergistic Cell Killing by Magnetic and Photoirradiation Effects of Neck-structured α-Fe2O3 against Cancer (HeLa) Cells

  • Md Shariful Islam
    Department of Chemistry and Bioscience, Graduate School of Science and Engineering, Kagoshima University
  • Yoshihumi Kusumoto
    Department of Chemistry and Bioscience, Graduate School of Science and Engineering, Kagoshima University
  • Md Abdulla-Al-Mamun
    Department of Chemistry and Bioscience, Graduate School of Science and Engineering, Kagoshima University
  • Yuji Horie
    Department of Electrical and Electronics Engineering, Graduate School of Science and Engineering, Kagoshima University

抄録

<jats:title>Abstract</jats:title> <jats:p>Nanosized neck-structured α-Fe2O3 nanoparticles were prepared successfully from iron(II) chloride tetrahydrate solely by hydrothermal method. FE-SEM and TEM studies revealed a unique necked structure with a particle size of ca. 50–60 nm. The synthesized nanomaterials showed excellent colloidal stability and magnetization ability. Finally, the as-prepared α-Fe2O3 nanoparticle suspensions showed almost 100% cancer cell killing by the significant temperature increment when an AC (alternating current) magnetic field and photoirradiation were applied at a concentration of 80 µg mL−1 MEM (minimum essential medium).</jats:p>

収録刊行物

  • Chemistry Letters

    Chemistry Letters 40 (7), 773-775, 2011-06-25

    Oxford University Press (OUP)

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