Thermal Stability of Synthetic Lipid Bicelles Encompassed by Siloxane Surfaces as Organic–Inorganic Hybrid Nanodiscs
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- Kazuma Yasuhara
- Graduate School of Materials Science, Nara Institute of Science and Technology
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- Hiroki Hayashi
- Graduate School of Materials Science, Nara Institute of Science and Technology
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- Jun-ichi Kikuchi
- Graduate School of Materials Science, Nara Institute of Science and Technology
抄録
<jats:title>Abstract</jats:title> <jats:p>We examined the thermal stability of organic–inorganic hybrid bicelles, which are lipid bilayer nanodiscs encompassed by siloxane surfaces. The hybrid bicelles were formed with a binary lipid mixture consisting of a long-chain alkoxysilane lipid and a short-chain phospholipid. It was clarified that the hybrid bicelles maintained a discoid assembly in water beyond the temperature of the gel to liquid-crystalline phase transition of the face-forming long-chain lipid, at which conventional phospholipid bicelles are transformed spontaneously to vesicles.</jats:p>
収録刊行物
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- Chemistry Letters
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Chemistry Letters 41 (10), 1223-1225, 2012-10
Oxford University Press (OUP)
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詳細情報 詳細情報について
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- CRID
- 1360002219111618048
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- NII論文ID
- 130004426360
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- ISSN
- 13480715
- 03667022
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