Practical Optical Resolution of Planar Chiral Pseudo-<i>ortho</i>-disubstituted [2.2]Paracyclophane

• Yasuhiro Morisaki

  Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University

• Ryoyu Hifumi

  Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University

• Lin Lin

  Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University

• Kenichi Inoshita

  Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University

• Yoshiki Chujo

  Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University

Abstract

We describe the practical optical resolution of rac-pseudo-ortho-dibromo[2.2]paracyclophane to obtain the parent compound for a variety of cyclophane-based planar chiral compounds such as enantiopure chiral ligand [2.2]PHANEPHOS. In addition, the obtained enantiopure planar chiral (R)- and (S)-pseudo-ortho-disubstituted [2.2]paracyclophanes can be used as the building blocks for optically active carbon-rich compounds.

Journal

• Chemistry Letters

  Chemistry Letters 41 (9), 990-992, 2012-09

  Oxford University Press (OUP)

Keywords

• General Chemistry

Details

• CRID: 1360846644041871616
• NII Article ID: 130004426698
• DOI: 10.1246/cl.2012.990
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/41/9/990/55635342/cl.2012.990.pdf
• Data Source:
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  • CiNii Articles
  • KAKEN