Synthesis of Monofluoromethylcyclopropanes from Alkenes without Using Freons: Novel Synthesis of Chlorofluoromethyl Phenyl Sulfide and Its Application in Cyclopropanation

• Masayuki Kirihara

  Department of Materials and Life Science, Shizuoka Institute of Science and Technology

• Tomomi Ogata

  Department of Materials and Life Science, Shizuoka Institute of Science and Technology

• Atsushi Itou

  Department of Materials and Life Science, Shizuoka Institute of Science and Technology

• Sayuri Naito

  Department of Materials and Life Science, Shizuoka Institute of Science and Technology

• Mari Kishida

  Department of Materials and Life Science, Shizuoka Institute of Science and Technology

• Kento Yamazaki

  Department of Materials and Life Science, Shizuoka Institute of Science and Technology

• Hidetsugu Tabata

  Faculty of Pharma Sciences, Teikyo University

• Hideyo Takahashi

  Faculty of Pharma Sciences, Teikyo University

Abstract

Chlorofluoromethyl phenyl sulfide was prepared from the reaction of chloromethyl phenyl sulfide with Selectfluor™. Monofluorocyclopropanation of an alkene was achieved via cyclopropanation using a fluorocarbene derived from the product chlorofluoromethyl phenyl sulfide, followed by oxidation and desulfurization.

Journal

• Chemistry Letters

  Chemistry Letters 42 (11), 1377-1379, 2013-07-20

  Oxford University Press (OUP)

Keywords

• General Chemistry

Details

• CRID: 1360283694082135680
• NII Article ID: 130004426837
• DOI: 10.1246/cl.130570
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/42/11/1377/55639901/cl.130570.pdf
• Data Source:
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  • CiNii Articles
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