Histopathological Changes in the Periphery of the Sciatic Nerve of Rats after Knee Joint Immobilization

DOI Web Site 被引用文献1件 参考文献9件
  • Yoshida Shinya
    Division of Rehabilitation, Kanazawa University Hospital: 13-1 Takaramachi, Kanazawa-shi, Ishikawa 920-8641, Japan
  • Matsuzaki Taro
    Division of Health Sciences, Kanazawa University Graduate School of Medical Science
  • Kamijo Akio
    Department of Rehabilitation Medicine, Azumino Red Cross Hospital
  • Araki Yoshitaka
    Department of Rehabilitation Medicine, Kanazawa Cranial Nerve Surgery Hospital
  • Sakamoto Makoto
    Department of Rehabilitation Medicine, Bobath Memorial Hospital
  • Moriyama Shigenori
    Division of Rehabilitation, Kanazawa University Hospital: 13-1 Takaramachi, Kanazawa-shi, Ishikawa 920-8641, Japan
  • Hoso Masahiro
    Division of Health Sciences, Kanazawa University Graduate School of Medical Science

この論文をさがす

抄録

[Purpose] This study was performed to investigate the histological changes that occur in the periphery of the sciatic nerve in rats undergoing knee immobilization. [Subjects and Methods] 29 male 9-week-old Wistar rats were divided randomly into a control group (C group, n = 7) and an immobilized group (I group, n = 22). The animals in the I group had the left knee joint immobilized in maximal flexion with plaster casts for two weeks. After the experimental period, we obtained cross-sections of tissues from the center of the left thigh, and the periphery of the sciatic nerve was observed under an optical microscope after hematoxylin-eosin staining. [Results] In contrast to the rats of C group, the rats in I group showed adherence between the bundle of nerve fibers and perineurium, as well as thickening of the perineurium. These histological changes were statistically significant. [Conclusions] Immobilization of the knee joints of rats resulted in characteristic histological changes in the connective tissue around the sciatic nerve.

収録刊行物

被引用文献 (1)*注記

もっと見る

参考文献 (9)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ