Structure of Guanethidine Monosulfate

TANAKA Rumiko, HARAMURA Masayuki, TANAKA Akito, HIRAYAMA Noriaki

doi:10.2116/analscix.21.x111

Structure of Guanethidine Monosulfate

DOI Web Site 参考文献2件

TANAKA Rumiko

Basic Medical Science and Molecular Medicine, Tokai University School of Medicine
HARAMURA Masayuki

Reverse Proteomics Research Institute Co. Ltd.
TANAKA Akito

Reverse Proteomics Research Institute Co. Ltd.
HIRAYAMA Noriaki

Basic Medical Science and Molecular Medicine, Tokai University School of Medicine

抄録

The crystal of the title compound, C₁₀H₂₂N₄·H₂SO₄, belongs to space group Pn with the cell dimensions a = 7.131(4), b = 12.969(6), c = 8.068(4)Å, and β = 110.32(3)°. The final R value is 0.063. The azocane ring adopts a boat-chair conformation. In a molecule, the N atom of the azocane ring and one of the N atoms of the guanidine group are bridged by a sulfate ion through a hydrogen bond. Hence, the ethylguanidine group takes a folded conformation. The ethylguanidine occupies an equatorial position of the ring.