Associations between the Autonomic Nervous System and the Second Derivative of the Finger Photoplethysmogram Indices

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Author(s)

    • Kohjitani Atsushi
    • Department of Dental Anesthesiology, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences
    • Miyata Masaaki
    • Department of Cardiovascular Medicine and Hypertension, Field of Cardiovascular and Respiratory Disorders, Kagoshima University Graduate School of Medical and Dental Sciences
    • Iwase Yoko
    • Department of Pediatric Dentistry, Niigata University Medical and Dental Hospital
    • Ohno Sachi
    • Department of Dental Anesthesiology, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences
    • Tohya Akina
    • Department of Dental Anesthesiology, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences
    • Manabe Yozo
    • Department of Dental Anesthesiology, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences
    • Hashiguchi Teruto
    • Department of Laboratory and Vascular Medicine, Field of Cardiovascular and Respiratory Disorders, Kagoshima University School of Medical and Dental Sciences
    • Sugiyama Kazuna
    • Department of Dental Anesthesiology, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences

Abstract

<b><i>Aim</i></b>: The indices of the second derivative of the finger photoplethysmogram(SDPTG) denote stiffness of large arteries, peripheral vascular resistance and vascular aging. However, the association between the autonomic nervous activity and the SDPTG indices has not yet been elucidated.<br><b><i>Methods</i></b>: The SDPTG and heart rate variability(HRV) were consecutively measured in the sitting position on the day before surgery in 168 patients 18-89 years of age. The relationships between the SDPTG indices(b/a, c/a, d/a and e/a) and HRV indices(power spectral analysis and time domain analysis parameters) were analyzed. The relationships between c/a and atherosclerosis-based conditions and risk factors for atherosclerosis were also evaluated.<br><b><i>Results</i></b>: The SDPTG index b/a was negatively associated and the d/a index was positively associated with the low-frequency(LF)(<i>R</i>=<b>−</b>0.44 and 0.42, respectively) and high-frequency(HF) components(<i>R</i>=<b>−</b>0.31 and 0.35, respectively). The SDPTG index c/a was also positively associated with the LF(<i>R</i>=0.40) and HF(<i>R</i>=0.44) components. A multivariate regression analysis showed that the LF, HF and heart rate were independent determinants of the c/a. Furthermore, the c/a values were significantly lower in the patients with hypertension, diabetes mellitus and hyperlipidemia than in those without these diseases, and a reduced c/a was significantly associated with increased serum triglyceride and total cholesterol concentrations.<br><b><i>Conclusions</i></b>: These findings suggest that a decrease in c/a is associated with a reduced baroreflex response of the peripheral vasomotor activity and a decreased cardiac parasympathetic activity. Furthermore, a decrease in c/a was found to be associated with atherosclerosis-based conditions, such as hypertension, diabetes mellitus and hyperlipidemia.

Journal

  • Journal of Atherosclerosis and Thrombosis

    Journal of Atherosclerosis and Thrombosis 21(5), 501-508, 2014

    Japan Atherosclerosis Society

Codes

  • NII Article ID (NAID)
    130004444730
  • Text Lang
    ENG
  • ISSN
    1340-3478
  • Data Source
    J-STAGE 
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