Population Based Cohort Study for Pediatric Infectious Diseases Research in Vietnam
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- Yoshida Lay-Myint
- Institute of Tropical Medicine, Nagasaki University
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- Suzuki Motoi
- Institute of Tropical Medicine, Nagasaki University
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- Thiem Vu Dinh
- National Institute of Hygiene and Epidemiology
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- Smith Wolf Peter
- London School of Tropical Medicine and Hygiene
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- Tsuzuki Ataru
- Institute of Tropical Medicine, Nagasaki University
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- Huong Vu Thi Thu
- National Institute of Hygiene and Epidemiology
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- Takahashi Kensuke
- Institute of Tropical Medicine, Nagasaki University
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- Miyakawa Masami
- Department of Pediatrics, Nagasaki University Hospital, Graduate School of Biomedical Sciences, Nagasaki University
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- Anh Nguyen Thi Hien
- National Institute of Hygiene and Epidemiology
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- Watanabe Kiwao
- Institute of Tropical Medicine, Nagasaki University
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- Ai Nguyen Thu Thuy
- Khanh Hoa General Hospital
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- Tho Le Huu
- KhanhHoa Provincial Public Health Service
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- Kilgore Paul
- College of Pharmacy and Health Sciences, Wayne State University
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- Yoshino Hiroshi
- Institute of Tropical Medicine, Nagasaki University
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- Toizumi Michiko
- Institute of Tropical Medicine, Nagasaki University
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- Yasunami Michio
- Institute of Tropical Medicine, Nagasaki University
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- Moriuchi Hiroyuki
- Department of Pediatrics, Nagasaki University Hospital, Graduate School of Biomedical Sciences, Nagasaki University
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- Anh Dang Duc
- National Institute of Hygiene and Epidemiology
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- Ariyoshi Koya
- Institute of Tropical Medicine, Nagasaki University
Abstract
A population-based cohort study on pediatric infectious diseases was established at Khanh Hoa Province, central Vietnam in 2006, to determine the etiology and risk factors for severe pediatric infectious diseases (SPID) such as acute respiratory infection (ARI), diarrhea and dengue which are the major causes of under 5 mortality. A population census survey was conducted in Nha-Trang and Ninh-Hoa to collect demographic, social-behavioral data and disease burden on SPID. The study site covered a population of 353,525 residing in 75,826 households with 24,781 children less than 5 years. Hospital databases from two hospitals covering the region were obtained. Linking the census and hospital databases, we were able to investigate on a variety of SPID such as environmental tobacco smoking exposure and increased risked of pediatric pneumonia hospitalization, population density, water supply and risk of dengue fever and animal livestock and risk of hospitalized diarrhea. To determine incidence, viral etiology and risk factors for pediatric ARI/pneumonia, we setup a population based prospective hospitalized Pediatric ARI surveillance at Khanh Hoa General Hospital, Nha-Trang in February 2007. The study has revealed RSV, rhinovirus and influenza A as major viral pathogens, role of multiple viral infection and its interaction with bacteria in the development of pneumonia. In addition, we are also conducting a birth cohort study to investigate the incidence of congenital infection and its impact on physical-neurological development, and role of host genetic polymorphism on SPID hospitalization in Vietnam. Population mobility, high cost of regular census update and low mortality are the challenges.
Journal
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- Tropical Medicine and Health
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Tropical Medicine and Health 42 (2SUPPLEMENT), S47-S58, 2014
Japanese Society of Tropical Medicine
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Details 詳細情報について
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- CRID
- 1390001205219154432
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- NII Article ID
- 130004463458
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- ISSN
- 13494147
- 13488945
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- HANDLE
- 10069/35285
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- Text Lang
- en
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- Data Source
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- JaLC
- IRDB
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed