Effect of semen characteristics on pregnancy rate following intrauterine insemination

• Dorjpurev Uranchimeg

  Department of Obstetrics and Gynecology, Institute of Health Biosciences, the University of Tokushima Graduate School

• Kuwahara Akira

  Department of Obstetrics and Gynecology, Institute of Health Biosciences, the University of Tokushima Graduate School

• Yano Yuya

  Department of Obstetrics and Gynecology, Institute of Health Biosciences, the University of Tokushima Graduate School

• Taniguchi Tomoko

  Department of Obstetrics and Gynecology, Institute of Health Biosciences, the University of Tokushima Graduate School

• Yamamoto Yuri

  Department of Obstetrics and Gynecology, Institute of Health Biosciences, the University of Tokushima Graduate School

• Suto Ayako

  Department of Obstetrics and Gynecology, Institute of Health Biosciences, the University of Tokushima Graduate School

• Tanaka Yu

  Department of Obstetrics and Gynecology, Institute of Health Biosciences, the University of Tokushima Graduate School

• Matsuzaki Toshiya

  Department of Obstetrics and Gynecology, Institute of Health Biosciences, the University of Tokushima Graduate School

• Yasui Toshiyuki

  Department of Obstetrics and Gynecology, Institute of Health Biosciences, the University of Tokushima Graduate School

• Irahara Minoru

  Department of Obstetrics and Gynecology, Institute of Health Biosciences, the University of Tokushima Graduate School

Abstract

Objective: To assess the effects of semen characteristics on the success of intrauterine insemination (IUI). Design: A retrospective study. Settings: The Department of Obstetrics and Gynecology, Tokushima University Hospital, Japan. Patients: Between 2004 and 2008, 1,177 IUI cycles in 283 couples were studied. Intervention: IUI cycles were preceded with ovarian stimulation. Main Outcome Measure: Clinical pregnancy. Result: A total of 82 clinical pregnancies were obtained (7.0% pregnancy rate per cycle, 28.9% per case). Their subsequent outcomes of pregnancies were 18 miscarriages (21.9%), 2 ectopic pregnancies (2.4%) and 60 live births (73.2%). Of the 82 clinical pregnancies, 2 were twin pregnancies (2.4%). There was no triple or higher order multiple pregnancies. At the end of the sixth cycle, 73 clinical pregnancies had been achieved (89.0%). After diagnostic laparoscopy, the pregnancy rate per cycle for patients ≤35 years age was 18%, which is significantly higher than that of patients >35 years of age. Pregnancies occurred up to the fifth cycle after laparoscopy. The pregnancy rate (PR) per cycle was significantly higher in cases of sperm movement rates more than 30% (PR 9.3%) and total motile sperm counts more than 10×10⁶/ml (PR 8.2%). A study comparing the washed and unwashed cases did not reveal any differences. Conclusion: In male sub-fertility cases of sperm parameters as motility rates ≥30% and motile sperm concentration ≥10×10⁶/ml, IUI could be a useful option for infertility treatment J. Med. Invest. 58: 127-133, February, 2011

Journal

• The Journal of Medical Investigation

  The Journal of Medical Investigation 58 (1,2), 127-133, 2011

  The University of Tokushima Faculty of Medicine

Keywords

• Intrauterine insemination
• sperm parameters
• diagnostic laparoscopy

Details

• CRID: 1390282679219615744
• NII Article ID: 130004465234
• NII Article ID: 80021578960
• NII Book ID: AA11166929
• DOI: 10.2152/jmi.58.127
• ISSN: 13496867
• ISSN: 13431420
• Web Site: http://repo.lib.tokushima-u.ac.jp/80826
• Web Site: http://www.jstage.jst.go.jp/article/jmi/58/1,2/58_1,2_127/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2012060863
• Text Lang: en
• Data Source:
  • JaLC
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed