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- Sasaki Masaya
- Division of Clinical Nutrition, Shiga University of Medical Science
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- Johtatsu Tomoko
- Division of Clinical Nutrition, Shiga University of Medical Science
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- Kurihara Mika
- Division of Clinical Nutrition, Shiga University of Medical Science
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- Iwakawa Hiromi
- Division of Clinical Nutrition, Shiga University of Medical Science
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- Tanaka Toshihiro
- Division of Clinical Nutrition, Shiga University of Medical Science
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- Tsujikawa Tomoyuki
- Department of Medicine, Shiga University of Medical Science
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- Fujiyama Yoshihide
- Department of Medicine, Shiga University of Medical Science
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- Andoh Akira
- Department of Medicine, Shiga University of Medical Science
抄録
We investigated energy expenditure in hospitalized patients with Crohn’s disease (CD), and determined optimal energy requirements for nutritional therapy. Sixteen patients (5 women and 11 men, mean age 36 year old, mean BMI 18.7 kg/m2) and 8 healthy volunteers were enrolled in this study. Measured resting energy expenditure (mREE) levels were determined by indirect calorimetry. The mREEs in CD patients were significantly higher than those of healthy controls (24.4 ± 2.4 kcal/kg/day vs 21.3 ± 1.7 kcal/kg/day). However, mREEs in CD patients were significantly lower than predicted REEs (pREEs) calculated by the Harris-Benedict equation (26.4 ± 2.5 kcal/kg/day). Furthermore, mREE/pREE values were lower in undernourished patients than in well-nourished patients. CD patients had hyper-metabolic statuses evaluated by mREE/body weight, but increased energy expenditure did not contribute to weight loss in these patients. In conclusion, nutritional therapy with 25–30 kcal/ideal body weight/day (calculated by mREE × active factor) may be optimal for active CD patients, while higher energy intake values pose the risk of overfeeding.<br>
収録刊行物
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- Journal of Clinical Biochemistry and Nutrition
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Journal of Clinical Biochemistry and Nutrition 46 (1), 68-72, 2009
一般社団法人 日本酸化ストレス学会
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詳細情報 詳細情報について
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- CRID
- 1390001204672234496
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- NII論文ID
- 130004466597
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- ISSN
- 18805086
- 09120009
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可