Perceptive Deafness by Fradiomycin Ointment in Two Burned Patients

DOI 1 Citations 4 References
  • TAKAHASHI Osamu
    Department of Dermatology, Tokushima University School of Medicine
  • TANAKA Shinji
    Department of Dermatology, Tokushima University School of Medicine
  • OGUNI Takashi
    Department of Dermatology, Tokushima University School of Medicine
  • NAKANISHI Hideki
    Department of Dermatology, Tokushima University School of Medicine

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Other Title
  • フラジオマイシン含有軟膏が原因と考えた両側感音難聴の2例

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Abstract

It is well known that the systemic application of a large amount of aminoglycoside antibiotics causes irreversible perceptive deafness. We report here two cases of perceptive deafness caused by the topical use of 0.2% Fradiomycin ointment onto burned surfaces of the skin. The burns were extensive and deep, in both cases. When the total amount of 38 kg and 48 kg of the ointment had been applied over a 4, 5 months period, tinnitus and perceptive deafness occurred. The symptoms were progressive for several months after cessation of the topical use of these ointments.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 48 (5), 892-896, 1986

    Western Division of Japanese Dermatological Association

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