Clear Cell Basal Cell Epithelioma  [in Japanese] Clear cell basal cell epithelioma.  [in Japanese]

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Author(s)

    • 佐藤 貴浩 SATOH Takahiro
    • 東京医科歯科大学医学部皮膚科学教室 Department of Dermatology, School of Medicine, Tokyo Medical and Dental University
    • 近藤 靖児 KONDO Seiji
    • 東京医科歯科大学医学部皮膚科学教室 Department of Dermatology, School of Medicine, Tokyo Medical and Dental University
    • 勝俣 道夫 KATSUMATA Michio
    • 東京医科歯科大学医学部皮膚科学教室 Department of Dermatology, School of Medicine, Tokyo Medical and Dental University

Abstract

36才女子の頭部に生じたclear cell basal cell epithelioma(以下clear cell BCEと略す)の1例を報告した。腫瘍塊は, 楕円形で胞体に乏しい好塩基性の細胞からなり, 腫瘍塊辺縁には柵状配列がみられた。一部の細胞は明調で, 微細顆粒状の胞体を有し, また, 小空胞や円形の空隙も認められた。これらの明調な細胞はPAS染色でわずかに陽性を呈したが, Sudan III染色では陰性であった。S100蛋白, CEAおよびリゾチームは検出されなかった。Clear cell BCEはBCEのまれな亜型として重要であると思われた。

A 36-year-old woman was seen at our hospital because of a slowly enlarging lesion of 2 years’ duration. Examination revealed a nodule of the size of a little finger’s head on the occipital region. Histologically, a circumscribed, non-encapsulated tumor composed of basophilic cells with peripheral palisading was located in the dermis. However, some of the tumor cells exhibited either a pale granular or clear cytoplasm. In these cells, many vacuoles of different sizes were found. While the cytoplasm of the clear cells showed negative for Sudan III, PAS produced a sparse positive staining. Neither S100 protein, carcinoembryonic antigen, nor lysozyme was detected. Based on these observations, our case was diagnosed as a clear cell basal cell epithelioma.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 52(2), 285-287, 1990

    Western Division of Japanese Dermatological Association

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