Preparation and in vitro apatite-forming ability of porous and non-porous titania microspheres
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- LI Zhixia
- School of Chemistry and Chemical Engineering, Guangxi University
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- MIYAZAKI Toshiki
- Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology
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- KAWASHITA Masakazu
- Graduate School of Biomedical Engineering, Tohoku University
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Abstract
Porous and non-porous titania microspheres with the anatase or rutile phase were successively prepared by the sol–gel process followed by heat treatment at various temperatures. The pore size of the prepared microspheres was effectively controlled by incorporating silica nanoparticles of different diameters. The apatite-forming ability of the microspheres was investigated in a simulated body fluid, with ion concentrations nearly equal to those of human blood plasma. Results indicated that the titania microspheres with either anatase or rutile structure induced the formation of calcium phosphate compounds (CaPs) on the microsphere surface. The deposition of CaPs was more pronounced on the TiO2 microspheres calcined at 600°C (anatase structure) and 800°C (rutile structure), compared to that calcined at 500°C (anatase structure). Additionally, anatase microspheres with smooth surface and low specific surface area favored the formation of CaPs, compared to porous microspheres. This indicates that nanoscale pores do not essentially favor apatite formation.
Journal
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- Journal of the Ceramic Society of Japan
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Journal of the Ceramic Society of Japan 121 (1417), 782-787, 2013
The Ceramic Society of Japan
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Details 詳細情報について
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- CRID
- 1390001205287875840
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- NII Article ID
- 130004480218
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- NII Book ID
- AA12229489
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- ISSN
- 13486535
- 18820743
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- HANDLE
- 10228/5918
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- Text Lang
- en
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- Data Source
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- JaLC
- IRDB
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed