-
- Asami Ayaji
- Graduate School of Oral Medicine, Matsumoto Dental University
-
- Nakamura Midori
- Department of Biochemistry, Matsumoto Dental University
-
- Takeuchi Mizuho
- Department of Pediatric Dentistry, Matsumoto Dental University
-
- Nakayama Akira
- Department of Pediatric Dentistry, Matsumoto Dental University
-
- Nakamura Hiroshi
- Department of Pediatric Dentistry, Matsumoto Dental University
-
- Yoshida Takamitsu
- Department of Dental Materials, Matsumoto Dental University
-
- Nagasawa Sakae
- Department of Pediatric Dentistry, Matsumoto Dental University
-
- Hiraoka B. Yukihiro
- Graduate School of Oral Medicine, Matsumoto Dental University
-
- Ito Michio
- Department of Dental Materials, Matsumoto Dental University
-
- Udagawa Nobuyuki
- Department of Biochemistry, Matsumoto Dental University
-
- Miyazawa Hiroo
- Graduate School of Oral Medicine, Matsumoto Dental University Department of Pediatric Dentistry, Matsumoto Dental University
この論文をさがす
抄録
To develop hydroxyapatite that promotes early cure of postoperative tissue, we heat-treated hydroxyapatite and evaluated its pH-increasing effect and Ca release. We also evaluated the effect of heat-treated hydroxyapatite on osteoblast differentiation. (1) No marked change was observed regarding the surface morphology or structure of heat-treated hydroxyapatite on SEM. (2) When hydroxyapatite was immersed in physiologic saline, the saline was made more alkaline by heat-treated than non-heat-treated hydroxyapatite. (3) When hydroxyapatite was immersed in physiologic saline, more Ca ions were released from heat-treated than non-heat-treated hydroxyapatite. (4) X-ray diffraction analysis showed a peak of CaO, which is considered to explain the Ca ion release, in heat-treated hydroxyapatite. (5) When osteoblasts were cultured with hydroxyapatite, heat-treated hydroxyapatite prevented the decrease in the number of alkaline phosphatase-positive osteoblasts in the presence of non-heat-treated hydroxyapatite. Thus, heat-treated hydroxyapatite was suggested to promote early cure of postoperative tissue. Detailed analysis of in vivo effects of heat-treated hydroxyapatite is anticipated to make its clinical application possible.
収録刊行物
-
- Journal of Hard Tissue Biology
-
Journal of Hard Tissue Biology 17 (2), 37-46, 2008
硬組織再生生物学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390001204457815552
-
- NII論文ID
- 130004480472
- 40016491557
-
- NII書誌ID
- AA11074332
-
- ISSN
- 1880828X
- 13417649
-
- NDL書誌ID
- 10181343
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可