Synthesis and Morphology of Platelet α-FeOOH and γ-Fe2O3 Nanoparticles for Cancer Therapy Using Hysteresis-Loss Heating

• Horiuchi A.

  Institute of Applied Physics, University of Tsukuba

• Seki A.

  Institute of Applied Physics, University of Tsukuba

• Isaka D.

  Institute of Applied Physics, University of Tsukuba

• Kishimoto M.

  Institute of Applied Physics, University of Tsukuba

• Yanagihara H.

  Institute of Applied Physics, University of Tsukuba

• Kita E.

  Institute of Applied Physics, University of Tsukuba

書誌事項

タイトル別名

• Synthesis and Morphology of Platelet α-FeOOH and γ-Fe₂O₃ Nanoparticles for Cancer Therapy Using Hysteresis-Loss Heating

抄録

The morphology of platelet α-FeOOH, a precursor for synthesizing γ-Fe₂O₃ particles for use in cancer therapy by hysteresis-loss heating, was investigated with the aim of reducing the size of γ-Fe₂O₃ particles. The α-FeOOH particles were synthesized by the precipitation of ferric ions in alkaline solution containing ethanolamine, and crystals were grown via hydrothermal treatment. The particle length of α-FeOOH was reduced on lowering the precipitation temperature and maintaining it in the range from −3°C to 6°C, whereas the ratio of the long and short axes was maintained. The axial ratio of the α-FeOOH particles was remarkably affected by the precipitant's aging temperature in the range of 4–60°C, and became smaller when the aging temperature was lowered. The addition of Si was effective for reduction of the particle length of α-FeOOH. Platelet α-FeOOH particles with a particle length of ~40 nm and an axial ratio of ~1.5 were obtained by using Si as an addictive and employing precipitation, aging, and hydrothermal treatment temperatures of −3.5°C, 4°C, and 150°C, respectively.

収録刊行物

• 粉体および粉末冶金

  粉体および粉末冶金 61 (S1), S125-S128, 2014

  一般社団法人 粉体粉末冶金協会

キーワード

• platelet nanoparticles
• α-FeOOH
• hysteresis-loss heating
• specific loss power
• thermoablation

詳細情報

• CRID: 1390282681286537728
• NII論文ID: 130004482649
• DOI: 10.2497/jjspm.61.s125
• ISSN: 18809014
• ISSN: 05328799
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可