Relationship between Autonomic Nervous System Activity during Sleep and Fasting Glucose in Japanese Workers

• KAMATA Naoki

  Department of Psychiatry, Graduate School of Medical Sciences, Kitasato University

• TANAKA Katsutoshi

  Department of Occupational Mental Health, Graduate School of Medical Sciences, Kitasato University

• MORITA Shiho

  Hygiene Management Center, Kakogawa Works, Kobe Steel, Ltd.

• TAGAYA Hirokuni

  Department of Health Science, School of Allied Health Sciences, Kitasato University

• KAWASHIMA Masatoshi

  Department of Preventive Medicine and Public Health, Graduate School of Medical Sciences, Kitasato University Graduate School

• SHICHIRI Masayoshi

  Department of Endocrinology, Diabetes and Metabolism, School of Medicine, Kitasato University

• MIYAOKA Hitoshi

  Department of Psychiatry, School of Medicine, Kitasato University

Abstract

Although autonomic nervous system activity is reportedly related to diurnal glucose tolerance impairment, the relationship with glucose tolerance during sleep is unclear. Since work styles have recently diversified, it is important to assess the effect of sleep on workers’ health. Elucidation of the relationship between autonomic nervous system activity during sleep and glucose tolerance in workers may facilitate preventive measures against diabetes using non-pharmacological means (e.g., sleep hygiene education, relaxation techniques and stress management). We examined whether autonomic nervous system activity during sleep is related to fasting glucose or glycated hemoglobin (HbA1c) in individuals with either normal or impaired fasting glucose tolerance. The subjects were 77 apparently healthy Japanese workers with normal or impaired fasting glucose. We used high frequency (HF) and the ratio of low frequency to high frequency (LF/HF) obtained by pulse wave analysis to estimate autonomic nervous system activity. The data were analyzed using a generalized estimating equation adjusted for potential confounders (age, gender, engagement in shift work, sleep duration, and body mass index). Fasting glucose was significantly negatively related to HF, the parasympathetic component during sleep. Our results suggest that parasympathetic activity during sleep is associated with fasting glucose in apparently healthy Japanese workers.<br>

Journal

• Industrial Health

  Industrial Health 49 (4), 427-433, 2011

  National Institute of Occupational Safety and Health

Keywords

• Autonomic nervous system activity
• Heart rate variability
• Fasting glucose
• HbA1c
• Frequency domain

Details

• CRID: 1390001204279326464
• NII Article ID: 40018947193
• NII Article ID: 130004483490
• NII Book ID: AA00672955
• DOI: 10.2486/indhealth.ms1257
• ISSN: 18808026
• ISSN: 00198366
• NDL BIB ID: 11199300
• PubMed: 21697626
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I11199300
• Web Site: https://www.jstage.jst.go.jp/article/indhealth/49/4/49_MS1257/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2012183474
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed