健康な犬におけるメチシリン耐性Staphylococcus pseudintermedius(MRSP)の疫学調査  [in Japanese] Epidemiological Study of Methicillin-resistant <i>Staphylococcus pseudintermedius</i> (MRSP) in Healthy Pet Dogs in Japan  [in Japanese]

Access this Article

Author(s)

Abstract

小動物臨床の高度化にともない広域抗菌薬が広く用いられるになり,メチシリン耐性 <i>Staphylococcus pseudintermedius</i>(MRSP)が犬に世界的に蔓延している。小動物皮膚科領域においてもMRSPは臨床上深刻な問題となっている。本研究では,日本国内の健康な犬104頭のMRSPおよびメチシリン耐性S. aureus (MRSA)の保菌調査を行い,二次診療施設(大学付属施設)を受診した病犬102頭の保菌率と比較した。健康犬および二次診療受診犬の鼻腔内MRSP保菌率はそれぞれ4.8%,21.6%(p<0.001)であり,二次診療受診犬で有意に高かった。二次診療受診犬は当該施設受診までに相当の抗菌薬選択圧を受けていることが示唆された。健康犬のMRSP保菌率は海外の報告とほぼ同等な結果であった。一方,MRSA保菌率は,健康犬で0%,二次診療受診犬で1.96%と両者に有意差はなかった。どのような抗菌薬選択圧下でもMRSA保菌率が有意に上昇しないことから,犬はMRSAのレゼルボアにはならないことが示唆された。<br>

In veterinary medicine, the use of broad-spectrum antibiotics has been increasing. The prevalence of methicillin-resistant <i>Staphylococcus pseudintermedius</i> (MRSP) in dogs is now increasingly common all over the world, and has also become a serious issue in veterinary dermatology practice in Japan. In the present study, we surveyed nasal carriage of MRSP and methicillin-resistant <i>S. aureus</i> (MRSA) in 104 healthy dogs in Japan, and compared the results with those of 102 patient dogs under secondary veterinary medical care. Nasal carriage rates of MRSP in healthy and patient dogs were 4.8% and 21.6%, respectively, and that of patient dogs was a significantly higher value (p<0.001), suggesting that patient dogs under secondary veterinary medical care were under antibiotic selective pressure. The MRSP carriage rate in healthy dogs in Japan was similar to those reported overseas. MRSA nasal carriage rates in healthy and patient dogs were 0% and 1.96%, respectively, with no significant difference between the two (p=0.244). Under antibiotic selective pressures, MRSA carriage rate in dogs didn’t increase significantly, suggesting that dogs have low potential as a reservoir of MRSA.<br>

Journal

  • The Japanese Journal of Veterinary Dermatology

    The Japanese Journal of Veterinary Dermatology 17(2), 79-83, 2011

    Japanese Society of Veterinary Dermatology

Keywords

Codes

  • NII Article ID (NAID)
    130004494299
  • Text Lang
    JPN
  • ISSN
    1347-6416
  • Data Source
    J-STAGE 
Page Top