慢性炎症より発生するBリンパ腫

DOI Web Site PubMed 被引用文献9件

書誌事項

タイトル別名
  • Non-Hodgkin's Lymphoma of the Pleural Cavity Developing from Long-standing Pyothorax
  • 慢性炎症より発生するBリンパ腫--胸膜リンパ腫を中心として
  • マンセイ エンショウ ヨリ ハッセイスル B リンパシュ キョウマク リンパシ
  • —胸膜リンパ腫を中心として—

この論文をさがす

抄録

Our previous study suggested a close relationship between a preceding chronic tuberculous pyothorax and the development of non-Hodgkin's lymphoma (NHL) in the pleural cavity. To confirm this further, 37 cases were collected, their clinical and pathological findings summarized. The age at first admission for lymphoma of patients ranged from 46 to 81 (mean 63) years, the male to female ratio being 5.2:1. All patients were admitted after a 22-55 (mean 33) year history of pyothorax resulting from artificial pneumothorax for treatment of pulmonary tuberculosis (29 cases) or tuberculous pleuritis (seven cases). The most common presenting symptom was chest pain. The diagnosis of pleural NHL was made by biopsy for 31 of the patients and at autopsy for the other six. Histologically 30 (81%) of 37 cases were of diffuse large cell type, and of these the immunoblastic type was the most common (22 cases). Immunological and immunohistologic studies revealed a B-cell nature of the proliferating cells in all but one tumor. Thirty-two patients received chemotherpy and/or radiotherapy. Twenty-seven patients died between one and 144 (median eight) months of diagnosis. Autopsies carried out in 23 cases revealed the disease to have been localized to the thorax in 11 patients. These findings indicated that malignant B-cell lymphoma arose as a monoclonal growth from a pool of proliferating polyclonal B lymphocytes in tissues affected by the chronic tuberculous pyothorax.

収録刊行物

  • 臨床血液

    臨床血液 31 (5), 547-553, 1990

    一般社団法人 日本血液学会

被引用文献 (9)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ