Lateral periodontal cyst: a clinicopathological study of 23 cases and an immunohistochemical analysis of its characteristic epithelial plaques in the lining

DOI 3 Citations 16 References
  • Tsuneki Masayuki
    Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences
  • Cheng Jun
    Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences
  • Yamazaki Manabu
    Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences
  • Maruyama Satoshi
    Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences
  • Kobayashi Takanori
    Surgical Pathology Section, Niigata University Hospital
  • Ida-Yonemochi Hiroko
    Surgical Pathology Section, Niigata University Hospital
  • Suzuki Makoto
    Surgical Pathology Section, Niigata University Hospital
  • Saku Takashi
    Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences Surgical Pathology Section, Niigata University Hospital

Search this article

Abstract

To characterize lateral periodontal cyst (LPC) clinicopathologically, we have analyzed 23 cases of LPC filed in Niigata University Hospital in the last 13 years. They accounted 1.4% of jaw cysts (1,683 cases total). The mean age of the patients was 46 years, and there were 13 male (56.5%) and 10 female (43.5%) patients. Maxillary LPCs were found in the incisor region, and mandibular ones were in the molar region. The maxillary cysts had larger size (19.8 mm, average diameter) and more frequent association with tooth roots (80%) than mandibular cysts (13.4 mm, 20%, respectively). Histopathologically, the linings of LPC were non-keratinized stratified squamous epithelia with occasional cuboidal changes containing small numbers of mucous or sebaceous cells. The base line of the lining epithelium was flat without rete processes. There were characteristic epithelial plaques (0.5 mm mean wide and 0.13 mm high) in all of the cases examined, and round or irregular-shaped epithelial islands were occasionally found in the cyst wall (34.8%). Immunohistochemically, there were scarcely any Ki-67-positive (+) cells in the lining epithelia, indicating that the lining cells were not proliferative. Both upper surface cells and basal cells of the epithelial plaques were CK19+ and integrin β1+, indicating that the epithelial plaques represented certain wrinkle or wavy protrusions of the inner surface of the cyst wall. The histopathological diagnosis of LPC must be precisely done from now on such clinicopathological characteristics are well recognized in this study.

Journal

Citations (3)*help

See more

References(16)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top