92歳で発症した劇症1型糖尿病の1例

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タイトル別名
  • A 92-year-old Patient with Fulminant Type 1 Diabetes
  • ショウレイ ホウコク 92サイ デ ハッショウ シタ ゲキショウ 1ガタ トウニョウビョウ ノ 1レイ

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A 92-year-old woman with senile dementia in a nursing home presented to the emergency department with tachypnea following loss of appetite that had lasted for two days. Diabetes mellitus had never been diagnosed. Urinalysis revealed ketonuria, and a serum glucose level of 986 mg/dl. Arterial blood gas analysis revealed anion gap metabolic acidosis. The patient was diagnosed as having diabetic ketoacidosis and insulin therapy was initiated, which proved effective. Other laboratory testing revealed a lack of insulin secretion, negative findings for islet-related autoantibodies, and a low hemoglobin A1c level of 6.4 %. These finding fulfill the diagnostic criteria of fulminant type 1 diabetes mellitus. A search of the literature in Japan showed that she was the oldest patient who had developed type 1 diabetes mellitus, including the non-fulminant subtypes. Physicians should remember that elderly patients with dementia, as in our case, might not exhibit the typical diabetic symptoms in the onset of fulminant type 1 diabetes mellitus.<br>

収録刊行物

  • 糖尿病

    糖尿病 55 (10), 793-797, 2012

    一般社団法人 日本糖尿病学会

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