Stem cells in dentistry—part I: stem cell sources.
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- Egusa Hiroshi
- Department of Fixed Prosthodontics, Osaka University Graduate School of Dentistry
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- Sonoyama Wataru
- Department of Oral Rehabilitation and Regenerative Medicine, Okayama University Graduate School Medicine, Dentistry and Pharmaceutical Sciences
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- Nishimura Masahiro
- Department of Prosthetic Dentistry, Graduate School of Biomedical Sciences, Nagasaki University
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- Atsuta Ikiru
- Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University
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- Akiyama Kentaro
- Department of Oral Rehabilitation and Regenerative Medicine, Okayama University Graduate School Medicine, Dentistry and Pharmaceutical Sciences
書誌事項
- タイトル別名
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- Stem cells in dentistry – Part I: Stem cell sources
- Stem cells in dentistry – Part I: stem cells sources
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抄録
Stem cells can self-renew and produce different cell types, thus providing new strategies to regenerate missing tissues and treat diseases. In the field of dentistry, adult mesenchymal stem/stromal cells (MSCs) have been identified in several oral and maxillofacial tissues, which suggests that the oral tissues are a rich source of stem cells, and oral stem and mucosal cells are expected to provide an ideal source for genetically reprogrammed cells such as induced pluripotent stem (iPS) cells. Furthermore, oral tissues are expected to be not only a source but also a therapeutic target for stem cells, as stem cell and tissue engineering therapies in dentistry continue to attract increasing clinical interest. Part I of this review outlines various types of intra- and extra-oral tissue-derived stem cells with regard to clinical availability and applications in dentistry. Additionally, appropriate sources of stem cells for regenerative dentistry are discussed with regard to differentiation capacity, accessibility and possible immunomodulatory properties.
収録刊行物
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- Journal of Prosthodontic Research
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Journal of Prosthodontic Research 56 (3), 151-165, 2012
公益社団法人 日本補綴歯科学会