鼻前庭炎の起炎菌について  [in Japanese] Bacteria involved in the inflammation of the nasal vestibule  [in Japanese]

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Abstract

鼻前庭炎患者 62 例の細菌検査を行った。その結果、黄色ブドウ球菌が 90.3%と圧倒的に多く MSSA は 40 例(64.5%)、MRSA は 16 例(25.8%)であった。他の細菌では CNS が 3例(4.8%)と続いたが、副鼻腔炎の起炎菌とされる菌種はまれであった。口角炎の起炎菌は唾液中に存在する菌であるのに対して、鼻前庭炎は鼻汁中の菌によって発症するものはまれで常在菌が何らかの刺激で活性化されて発症するものと考えた。活性化する原因は鼻前庭炎の発症時期が冬季と花粉症の時期に多く、夏季に少ないことより鼻炎、感冒との関連で鼻を触ることが原因と推察した。MSSA で最も有効な抗生剤は FMOX(100%)で、次いで MINO(97.5%)、CAM(72.5%)であった。MRSA の中でも MINO が有効であったのは 16 例中 10 例(62.5%)であり、60 歳以上の鼻前庭炎症例では 6 例(37.5%)すべてが MINO に感受性のない MRSA であった。

We investigated the bacteria present in 62 cases of inflammation of the nasal vestibule. <i>Staphylococcus aureus</i> was the most frequently observed bacterium, and was present in 56 cases (90.3%). MSSA (methicillin-sensitive Staphylococci) were found in 40 cases (64.5%) and MRSA (methicillin-resistant Staphylococci) were found in 16 cases (25.8%). CNS (coagulase-negative Staphylococci) were present in three cases. Bacteria that cause sinusitis were rarely observed. We consider that angular cheilitis is often caused by the bacteria preset in saliva, while inflammation of the nasal vestibule is not caused by bacteria in nasal discharge, but by the normal flora following activation by some type of stimulus. The stimulation might be related to allergic rhinitis or the common cold, because it often occurs during the pollinosis season or in the winter, and rarely in the summer. The most effective antibiotic against MSSA was FMOX (100%), followed by MINO (97.5%). MRSA is classified into communityacquired MRSA (CA-MRSA), which is sensitive to MINO, and into hospital-acquired MRSA (HA-MRSA), which is resistant to most antibiotics. CA-MRSA accounted for 10 out of 16 cases of MRSA (62.5%). A high percentage (30.1%) of the patients older than 60 years showed MRSA colonization, and all six cases of HA-MRSA were included in this age group.

Journal

  • jibi to rinsho

    jibi to rinsho 59(3), 108-114, 2013

    JIBI TO RINSHO KAI

Keywords

Codes

  • NII Article ID (NAID)
    130004555609
  • Text Lang
    JPN
  • ISSN
    0447-7227
  • Data Source
    J-STAGE 
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