Automated Cardiovascular Drug Infusion System to Control Hemodynamics

• UEMURA Kazunori

  Department of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center Research Institute

• SUGIMACHI Masaru

  Department of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center Research Institute

抄録

In the management of patients with unstable hemodynamics as seen in myocardial infarction or after cardiac surgical procedures, cardiovascular drugs such as inotropes and/or vasodilators are commonly infused to control systemic arterial pressure and/or cardiac output. Since responses to these agents vary between patients and within patient over time, strict monitoring of patient condition and frequent adjustments of drug infusion rates are usually required. This is a difficult and time-consuming process. Closed-loop systems to automate drug infusion have been developed to facilitate this process. In the clinical setting, although closed-loop control of hemodynamics has been suggested to be useful and improve patient outcomes, this approach has not yet been widely adopted. In this review, we introduce several closed-loop systems that have been developed so far and our novel approach to control overall hemodynamics, address issues in their clinical application, and discuss future perspectives in this field.

収録刊行物

• Advanced Biomedical Engineering

  Advanced Biomedical Engineering 2 (0), 32-37, 2013

  公益社団法人 日本生体医工学会

キーワード

• closed-loop control
• cardiovascular drug
• hemodynamics

詳細情報

• CRID: 1390282680480398592
• NII論文ID: 130004568019
• DOI: 10.14326/abe.2.32
• ISSN: 21875219
• Web Site: https://www.jstage.jst.go.jp/article/abe/2/0/2_32/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2015213485
• 本文言語コード: en
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