小児移植医療―小腸移植  [in Japanese] Intestinal transplantation for children  [in Japanese]

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Author(s)

    • 和田 基 Wada Motoshi
    • 東北大学病院小児外科学分野 Department of Pediatric Surgery, Tohoku University School of Medicine
    • 仁尾 正記 Nio Masaki
    • 東北大学病院小児外科学分野 Department of Pediatric Surgery, Tohoku University School of Medicine

Abstract

Although the development of parenteral nutrition has improved outcomes of intestinal failure, parenteral nutrition still often leads to numerous life-threatening complications. Intestinal failure-associated liver disease (IFALD), which can be progressive and fatal in children, is one of the most serious complications. Intestinal transplantation (Itx) represents a definitive treatment for patients with irreversible intestinal failure. By 2013, a total of 2887 intestinal transplants had been performed worldwide, 55% of which were in patients under 18 years old. In Japan, 60% of all recipients were under 18 years old. Because of recent advances in the management of Itx, short-term outcomes following transplantation have improved; however, the long-term outcomes remain insufficient. Furthermore, some patients with severe IFALD require liver-intestinal transplantation, a procedure that remains practically unavailable in Japan. In this article, we provide an overview of the process and the problems of pediatric Itx, with special focus on the situation in Japan.

Journal

  • Japanese Journal of Transplantation

    Japanese Journal of Transplantation 49(2-3), 215-223, 2014

    The Japan Society for Transplantation

Codes

  • NII Article ID (NAID)
    130004640154
  • Text Lang
    JPN
  • ISSN
    0578-7947
  • Data Source
    J-STAGE 
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