Cytological Features and Significance of Multinucleated Giant Cells in Inflammatory Colorectal Polyps of Miniature Dachshund

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  • ミニチュア・ダックスフンドの炎症性結直腸ポリープの細胞学的特徴と多核巨細胞の診断的意義
  • ミニチュア ・ ダックスフンド ノ エンショウセイ ケツ チョクチョウ ポリープ ノ サイボウガクテキ トクチョウ ト タカクキョサイボウ ノ シンダンテキ イギ

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Abstract

For establishment of cytological diagnostic criteria of inflammatory colorectal polyp (ICRP) in miniature dachshunds (M. dax), cytological specimens of 16 cases of ICRP of M. dax (ICRP group) and 53 cases of a non-ICRP group including normal mucosa, inflammatory diseases and neoplastic diseases were analyzed. In 12 cases of the ICRP group (75.0%), significantly more multinucleated giant cells (MGCs) were detected than those in the non-ICRP group (only one case, 1.9%). Sensitivity, specificity, positive predictive value and negative predictive value of cytological detection of MGCs in cytological specimens to diagnose ICRP were 75.0%, 98.2%, 92.3% and 93.2%, respectively. In conclusion,detection of MGCs in colorectal cytology of M. dax is useful for cytological diagnosis of ICRP.

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