Nano-Particle Positioning on DNA Strand

• Osanai Hiroshi

  Tokyo Institute of Technology

• Yanagida Yasuko

  Tokyo Institute of Technology

• Hatsuzawa Takeshi

  Tokyo Institute of Technology

Bibliographic Information

Other Title

• DNAを用いたナノ粒子の位置決め
• 対合効率と長鎖化の検討

Abstract

A novel nano–mechanism assemble technique using DNA strand and chemically modified gold nano–particles has been improved. Four types of DNA short single strand has been synthesized and hybridized to form two unit–blocks of the nano–mechanism. Each type of blocks has non–palindrome sticky end to connect them in turn and one of the unit–blocks is labeled by gold nano–particle. We calculate to design DNA sequence that is high efficiency in hybridization. After ligating the unit–blocks by ligase, a long strand of DNA chain with periodic nano–particle can be assembled. AFM micrographs show serial nano–particle chains with pitches of almost 27nm. This result indicates the usefulness of the proposed technique for nano–mechanism assembling.

Journal

• Proceedings of JSPE Semestrial Meeting

  Proceedings of JSPE Semestrial Meeting 2005A (0), 949-950, 2005

  The Japan Society for Precision Engineering

Keywords

• nano structure
• nano particle
• nano beads
• DNA

Details

• CRID: 1390282680625264640
• NII Article ID: 130004657255
• DOI: 10.11522/pscjspe.2005a.0.949.0
• Data Source:
  • JaLC
  • CiNii Articles
• Abstract License Flag: Disallowed