進歩し続けるグリコシル化反応とオリゴ糖合成

• 野上 敏材

  鳥取大学大学院工学研究科

書誌事項

タイトル別名

• Recent Progress of Chemical Glycosylations and Oligosaccharide Synthesis
• シンポ シ ツズケル グリコシルカ ハンノウ ト オリゴトウ ゴウセイ

抄録

Development of chemical glycosylations is crucial to achieve effective synthesis of biologically important oligosaccharides and glycoconjugates in a large amount with high purity. Although tremendous efforts have been done to synthesize complex oligosaccharides for more than several decades, numbers of reliable and versatile methods for chemical glycosylations are limited. Solid-phase synthesis does not seem to be the final answer for oligosaccharide synthesis and automated synthesizers for oligosaccharides in solution-phase are still under development. Therefore, it is particularly important to review recent progress of methodologies for chemical glycosylations carefully and figure out what is a challenge in this research field. In this review article, recent development of glycosylation methods and novel strategies for oligosaccharide synthesis is highlighted from the viewpoint of a synthetic organic chemist.

収録刊行物

• 有機合成化学協会誌

  有機合成化学協会誌 72 (7), 797-807, 2014

  公益社団法人 有機合成化学協会

キーワード

• glycosylation
• oligosaccharide
• glycosidic linkage
• oligosaccharide synthesis
• automated synthesis
• glycosylation intermediate

詳細情報

• CRID: 1390001205339936512
• NII論文ID: 130004679610
• NII書誌ID: AN0024521X
• DOI: 10.5059/yukigoseikyokaishi.72.797
• ISSN: 18836526
• ISSN: 00379980
• NDL書誌ID: 025635387
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I025635387
• 本文言語コード: ja
• データソース種別:
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  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可