Nanobiodevice-based Single Biomolecule Analysis, Single-Cell Analysis, and in vivo Imaging for Cancer Diagnosis, Cancer Theranostics, and iPS Cell-based Regenerative Medicine

• KAJI Noritada

  Department of Applied Chemistry, Graduate School of Engineering, FIRST Research Center for Innovative Nanobiodevices, and Institute of Innovation for Future Society, Nagoya University

• BABA Yoshinobu

  Department of Applied Chemistry, Graduate School of Engineering, FIRST Research Center for Innovative Nanobiodevices, and Institute of Innovation for Future Society, Nagoya University Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)

書誌事項

タイトル別名

• Nanobiodevice-based Single Biomolecule Analysis, Single-Cell Analysis, and <i>in vivo</i> Imaging for Cancer Diagnosis, Cancer Theranostics, and iPS Cell-based Regenerative Medicine

抄録

Numerous nanobiodevices have been developed for cancer diagnosis through the analysis of cancer cells and cancer-related biomolecules, cancer gene therapy, and iPS cell-based regenerative medicine. A microchamber array, which is fabricated on a plastic chip, enables to develop a reliable circulating tumor cell (CTC) detection technique for cancer metastasis diagnosis. A nanopillar-array or a nanowire-array on a quartz chip allows ultrafast analysis of DNA and microRNA within 1 s for the molecular diagnosis of cancer. Immunopillar devices, which contain a tremendous amount of antibody-immobilized microparticles inside an immunopillar structure, have realized fast and low invasive “from blood to analysis” type biomarker detection of cancer with a pM detection sensitivity within 5 min. Quantum dots and gene delivery nanodevices are applied to single cancer cell diagnosis, in vivo imaging for iPS cell based regenerative medicine, and theranostic devices for cancer diagnosis and therapy.

収録刊行物

• Analytical Sciences

  Analytical Sciences 30 (9), 859-864, 2014

  社団法人 日本分析化学会

キーワード

• Nanobiodevices
• single biomolecule analysis
• single cell analysis
• quantum dots

詳細情報

• CRID: 1390001204260579200
• NII論文ID: 130004687411
• NII書誌ID: AA10500785
• DOI: 10.2116/analsci.30.859
• COI: 1:STN:280:DC%2BC2M7gslKjtQ%3D%3D
• ISSN: 13482246
• ISSN: 09106340
• NDL書誌ID: 025775288
• PubMed: 25213813
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I025775288
• Web Site: https://link.springer.com/content/pdf/10.2116/analsci.30.859.pdf
• Web Site: https://link.springer.com/article/10.2116/analsci.30.859/fulltext.html
• Web Site: https://www.jstage.jst.go.jp/article/analsci/30/9/30_859/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2015159926
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可