Isoxazole Platform for Polyketide Assembly: Cycloaddition of Stable Benzonitrile Oxides to Stable <i>ortho</i>-Quinone Monoacetals and Dehydrogenation

• Hiroshi Takikawa

  Department of Chemistry, Tokyo Institute of Technology

• Yoshimitsu Hashimoto

  Department of Chemistry, Tokyo Institute of Technology

• Keisuke Suzuki

  Department of Chemistry, Tokyo Institute of Technology

Abstract

A two-step preparation of highly functionalized polycyclic isoxazoles is described via regioselective 1,3-dipolar cycloaddition of ortho-disubstituted benzonitrile oxides to ortho-quinone monoacetals and dehydrogenation by NiO2.

Journal

• Chemistry Letters

  Chemistry Letters 43 (10), 1607-1609, 2014-07-03

  Oxford University Press (OUP)

Keywords

• General Chemistry

Details

• CRID: 1360565169058994048
• NII Article ID: 130004693826
• DOI: 10.1246/cl.140574
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/43/10/1607/55644151/cl.140574.pdf
• Data Source:
  • Crossref
  • CiNii Articles
  • KAKEN