Adding Coronary Computed Tomography Angiography to Invasive Coronary Angiography Improves Prediction of Cardiac Events
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- Kawai Hideki
- Department of Cardiology, Fujita Health University
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- Motoyama Sadako
- Department of Cardiology, Fujita Health University
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- Sarai Masayoshi
- Department of Cardiology, Fujita Health University
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- Ito Hajime
- Department of Cardiology, Fujita Health University
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- Takahashi Hiroshi
- Department of Medical Statistics, Fujita Health University
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- Harigaya Hiroto
- Department of Cardiology, Nagoya Memorial Hospital
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- Kan Shino
- Department of Cardiology, Nagoya Memorial Hospital
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- Ishii Junichi
- Department of Cardiology, Fujita Health University
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- Anno Hirofumi
- Department of Radiology, Fujita Health University
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- Murohara Toyoaki
- Department of Cardiology, Nagoya University Graduate School of Medicine
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- Ozaki Yukio
- Department of Cardiology, Fujita Health University
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Background:The additive value of plaque characteristics determined by computed tomography angiography (CTA) in patients undergoing invasive coronary angiography (ICA) has not been established.Methods and Results:We studied 676 patients undergoing ICA and CTA within 3 months. The luminal diameter narrowing based on ICA and the presence of high risk plaque (HRP) based on CTA were assessed in all coronary artery segments except for those after or before scheduled treatment. We followed their cardiac events including cardiac death, acute coronary syndrome (ACS), and revascularization for de novo lesions ≥3 months after ICA. The incidence of coronary events was higher in the segments including >25% luminal narrowing than in those without (2.94% vs. 0.31%, P<0.0001), and higher in the segments containing HRP than in those without (12.6 vs. 0.46%, P<0.0001). Greater than 25% residual luminal narrowing and the presence of HRP were identified as independent predictors of cardiac events after risk adjustment for age, gender, and history of ACS (hazard ratio [HR], 3.22; 95% confidence interval [CI]: 1.29–10.76; P=0.0092, HR, 2.64; 95% CI: 1.59–4.35; P=0.0002, respectively). Adding the presence of HRP to a model including age, gender, ACS history, and >25% residual stenosis improved the prediction of cardiac events.Conclusions:Assessment of coronary plaque characteristics on CTA improves the prediction of cardiac events in patients undergoing ICA. (Circ J 2014; 78: 2735–2740)
収録刊行物
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- Circulation Journal
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Circulation Journal 78 (11), 2735-2740, 2014
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390001205107714176
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- NII論文ID
- 130004693866
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- NII書誌ID
- AA11591968
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- COI
- 1:STN:280:DC%2BC2M7osleqsw%3D%3D
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 025863024
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- PubMed
- 25298167
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 使用不可