Evaluation of Stress related to Invasive Medical Procedures in Children With Cancer using Salivary α-Amylase Activity

DOI Web Site 30 References
  • Fukasawa Mikae
    Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan
  • Shimomura Yukiko
    Center for children with Intellectual Disabilities, Kawasaki-shi Shiinoki Gakuen, Japan
  • Takeda Kazunori
    Institute of Disability Sciences, University of Tsukuba, Japan

Search this article

Abstract

The purpose of this study is to investigate the usefulness of salivary α-amylase activity (sAA) as an index of stress related to invasive medical procedure in children with cancer. sAA and heart rate (HR) were measured before and after bone marrow aspirations or lumbar punctures in pediatric cancer inpatients. Child's self-report, parents' and physicians' reports were also collected to evaluate children's fear and distress during the procedure. As a result, sAA immediately before and immediately after procedure were significantly higher than 30 minutes before procedure and after recovery from sedation. HR showed no significant differences. Physician's rating of child distress was significantly related with sAA. In this study, sAA was shown to sensitively reflect children's physical and mental stress, and was measurable non-invasively and easily. It can be a useful index of stress related to invasive medical procedure in children with cancer.

Journal

References(30)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top