Diffusion-weighted Line-scan Echo-planar Spectroscopic Imaging Technique to Reduce Motion Artifacts in Metabolite Diffusion Imaging
-
- BITO Yoshitaka
- Central Research Laboratory, Hitachi, Ltd. MRI System Division, Hitachi Medical Corporation Faculty of Engineering, Graduate School of Engineering, Chiba University
-
- HIRATA Koji
- Central Research Laboratory, Hitachi, Ltd.
-
- EBISU Toshihiko
- Department of Neurosurgery, Nantan General Hospital
-
- KAWAI Yuko
- Department of Medical Informatics, Meiji University of Integrative Medicine
-
- OTAKE Yosuke
- Central Research Laboratory, Hitachi, Ltd.
-
- HIRATA Satoshi
- Central Research Laboratory, Hitachi, Ltd.
-
- SHIRAI Toru
- Central Research Laboratory, Hitachi, Ltd.
-
- SOUTOME Yoshihisa
- Central Research Laboratory, Hitachi, Ltd.
-
- OCHI Hisaaki
- Central Research Laboratory, Hitachi, Ltd.
-
- YAMAMOTO Etsuji
- Faculty of Engineering, Graduate School of Engineering, Chiba University
-
- UMEDA Masahiro
- Department of Medical Informatics, Meiji University of Integrative Medicine
-
- HIGUCHI Toshihiro
- Department of Neurosurgery, Meiji University of Integrative Medicine
-
- TANAKA Chuzo
- Department of Neurosurgery, Meiji University of Integrative Medicine
この論文をさがす
抄録
Metabolite diffusion is expected to provide more specific microstructural and functional information than water diffusion. However, highly accurate measurement techniques have still not been developed, especially for reducing motion artifacts caused by cardiac pulsation and respiration. We developed a diffusion-weighted line-scan echo-planar spectroscopic imaging (DW-LSEPSI) technique to reduce such motion artifacts in measuring diffusion-weighted images (DWI) of metabolites. Our technique uses line-scan and echo-planar techniques to reduce phase errors induced by such motion during diffusion time. The phase errors are corrected using residual water signals in water suppression for each acquisition and at each spatial pixel specified by combining the line-scan and echo-planar techniques. We apply this technique to a moving phantom and a rat brain in vivo to demonstrate the reduction of motion artifacts in DWI and apparent diffusion coefficient (ADC) maps of metabolites. DW-LSEPSI will be useful for investigating a cellular diffusion environment using metabolites as probes.
収録刊行物
-
- Magnetic Resonance in Medical Sciences
-
Magnetic Resonance in Medical Sciences 14 (1), 43-50, 2015
日本磁気共鳴医学会